Reactome | SHC1 binds P-ERBB4 isoform dimers

SHC1 binds P-ERBB4 isoform dimers

Stable Identifier

R-HSA-1250357

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol, extracellular region

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Phosphorylated tyrosine residues in the C-tail of phosphorylated ERBB4 isoform dimers P-ERBB4jmAcyt1, P-ERBB4jmAcyt2 and P-ERBB4jmBcyt1 recruit SHC1 (Cohen et al. 1996, Pinkas-Kramarski et al. 1996, Kaushansky et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
8665853	Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions Pinkas-Kramarski, R, Soussan, L, Waterman, H, Levkowitz, G, Alroy, I, Klapper, L, Lavi, S, Seger, R, Ratzkin, BJ, Sela, M, Yarden, Y	EMBO J	1996
18721752	System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties Kaushansky, A, Gordus, A, Budnik, BA, Lane, WS, Rush, J, MacBeath, G	Chem Biol	2008
8617750	HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence for HER1-HER4 heterodimers Cohen, BD, Green, JM, Foy, L, Fell, HP	J Biol Chem	1996