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YAP1 [nucleoplasm]
Stable Identifier
R-HSA-1253322
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Developmental Cell Lineages (Homo sapiens)
Differentiation of keratinocytes in interfollicular epidermis in mammalian skin (Homo sapiens)
Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis (Homo sapiens)
keratinocyte stem cell of skin epidermis basal layer (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of axial mesoderm (Homo sapiens)
Expression of FOXA2 in the anterior primitive streak (Homo sapiens)
TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] (Homo sapiens)
TEAD2:YAP1,TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Expression of NOTO in axial mesoderm (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene (Homo sapiens)
TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] (Homo sapiens)
TEAD2:YAP1,TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1,TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Zygotic genome activation (ZGA) (Homo sapiens)
Expression of TUT4 in the embryo (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Expression of TUT7 in the embryo (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Nervous system development (Homo sapiens)
EGR2 and SOX10-mediated initiation of Schwann cell myelination (Homo sapiens)
EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene (Homo sapiens)
PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:WWTR1,YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:WWTR1,YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
PMP22 gene expression (Homo sapiens)
PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:WWTR1,YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Homo sapiens)
ABL1 phosphorylates YAP1 (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
ITCH gene expression is stimulated by RUNX1 and YAP1 (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:YAP1:ITCH gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
RUNX1 binds YAP1 (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
The complex of RUNX1 and YAP1 binds the ITCH gene promoter (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:YAP1:ITCH gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX3 (Homo sapiens)
RUNX3 regulates YAP1-mediated transcription (Homo sapiens)
Expression of CTGF (Homo sapiens)
TEADs:YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
RUNX3 binds TEADs and YAP1 (Homo sapiens)
RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEADs:YAP1 binds CTGF gene (Homo sapiens)
RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEADs:YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEADs:YAP1:CTGF gene [nucleoplasm] (Homo sapiens)
TEADs:YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1- and WWTR1 (TAZ)-stimulated gene expression (Homo sapiens)
Expression of CTGF (Homo sapiens)
TEADs:YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 binds TEAD1 (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 binds TEAD2 (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 binds TEAD3 (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 binds TEAD4 (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Hippo (Homo sapiens)
Translocation of YAP1 to the nucleus (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Homo sapiens)
YAP1:TJP2 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
Nuclear signaling by ERBB4 (Homo sapiens)
Translocation of ERBB4s80:YAP1 complex to the nucleus (Homo sapiens)
ERBB4s80:YAP1 [nucleoplasm] (Homo sapiens)
YAP1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46937 YAP1
Gene Names
YAP1, YAP65
Chain
chain:1-504
Reference Genes
BioGPS Gene:10413 YAP1
COSMIC (genes):YAP1 YAP1
CTD Gene:10413 YAP1
dbSNP Gene:10413 YAP1
ENSEMBL:ENSG00000137693 YAP1
ENSEMBL_homo_sapiens_GENE:ENSG00000137693.14 YAP1
HGNC:16262 YAP1
KEGG Gene (Homo sapiens):10413 YAP1
Monarch:10413 YAP1
NCBI Gene:10413 YAP1
OMIM:606608 YAP1
UCSC:P46937 YAP1
Reference Transcript
RefSeq:NM_001282097.1 YAP1
RefSeq:NM_001282098.1 YAP1
RefSeq:NM_001282100.1 YAP1
RefSeq:NM_001282099.1 YAP1
RefSeq:NM_001282101.1 YAP1
RefSeq:NM_001130145.2 YAP1
RefSeq:NM_001195044.1 YAP1
RefSeq:NM_001195045.1 YAP1
Other Identifiers
10413
11717920_a_at
11717921_x_at
11717922_a_at
11717923_s_at
11717924_a_at
11717925_s_at
11740548_a_at
11746496_a_at
16730503
213342_PM_at
213342_at
224894_PM_at
224894_at
224895_PM_at
224895_at
2929983
3346452
3346454
3346455
3346456
3346457
3346458
3346460
3346461
3346468
3346479
3346489
3346492
3346498
3346504
3346508
3346509
3346510
37979_at
46314_at
7943398
A_14_P102030
A_23_P104762
A_24_P273679
GE60063
GO:0000122
GO:0000902
GO:0000976
GO:0000978
GO:0001570
GO:0001674
GO:0001824
GO:0001829
GO:0001894
GO:0002067
GO:0003013
GO:0003015
GO:0003143
GO:0003677
GO:0003682
GO:0003713
GO:0003714
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0005829
GO:0005911
GO:0006351
GO:0006355
GO:0006974
GO:0008283
GO:0008284
GO:0010468
GO:0010628
GO:0010629
GO:0010837
GO:0012501
GO:0016020
GO:0023052
GO:0030054
GO:0030154
GO:0030216
GO:0030307
GO:0030857
GO:0030859
GO:0030903
GO:0032570
GO:0033148
GO:0035019
GO:0035265
GO:0035329
GO:0042060
GO:0042127
GO:0043226
GO:0044782
GO:0045599
GO:0045669
GO:0045747
GO:0045893
GO:0045944
GO:0046622
GO:0048339
GO:0048368
GO:0048856
GO:0050673
GO:0050679
GO:0050767
GO:0050847
GO:0060045
GO:0060070
GO:0060242
GO:0060449
GO:0060487
GO:0060575
GO:0060576
GO:0060828
GO:0061026
GO:0065003
GO:0070064
GO:0070102
GO:0070161
GO:0071300
GO:0071480
GO:0072091
GO:0072307
GO:0090263
GO:0097191
GO:0140110
GO:0140297
GO:0140552
GO:1900182
GO:1902018
GO:1902459
GO:1903703
GO:1904036
GO:2000737
GO:2001237
HMNXSV003031607
Hs.84520.0.S1_3p_at
Hs.84520.0.S2_3p_at
Hs.8939.0.A2_3p_at
ILMN_1709479
PH_hs_0022813
TC11000954.hg
X80507_at
Participates
as a protein marker of
keratinocyte stem cell of skin epidermis basal layer (Homo sapiens)
as a component of
ERBB4s80:YAP1 [nucleoplasm] (Homo sapiens)
YAP1:TJP2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:YAP1 [nucleoplasm] (Homo sapiens)
TEAD2:YAP1 [nucleoplasm] (Homo sapiens)
TEAD3:YAP1 [nucleoplasm] (Homo sapiens)
YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] (Homo sapiens)
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
TEAD1:YAP1 [nucleoplasm] (Homo sapiens)
as an input of
ABL1 phosphorylates YAP1 (Homo sapiens)
RUNX1 binds YAP1 (Homo sapiens)
YAP1 binds TEAD2 (Homo sapiens)
YAP1 binds TEAD4 (Homo sapiens)
YAP1 binds TEAD3 (Homo sapiens)
YAP1 binds TEAD1 (Homo sapiens)
as an output of
Translocation of YAP1 to the nucleus (Homo sapiens)
Other forms of this molecule
p-Y407-YAP1 [cytosol]
p-S127-YAP1 [cytosol]
p-5S-YAP1 [cytosol]
p-Y407-YAP1 [nucleoplasm]
p-Y-YAP1 [cytosol]
p-Y-YAP1 [nucleoplasm]
YAP1 [cytosol]
Inferred To
Yap1 [nucleoplasm]
(Mus musculus)
Yap1 [nucleoplasm]
(Rattus norvegicus)
yap-1 [nucleoplasm]
(Caenorhabditis elegans)
yap1 [nucleoplasm]
(Danio rerio)
yap1 [nucleoplasm]
(Xenopus tropicalis)
YAP1 [nucleoplasm]
(Bos taurus)
YAP1 [nucleoplasm]
(Canis familiaris)
YAP1 [nucleoplasm]
(Gallus gallus)
YAP1 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001269029.1
,
NP_001269026.1
,
NP_001269027.1
,
NP_001181974.1
,
NP_001181973.1
,
NP_001123617.1
,
NP_001269028.1
,
NP_001269030.1
OpenTargets
ENSG00000137693
GeneCards
P46937
HPA
ENSG00000137693-YAP1
Ensembl
ENSP00000434134
,
ENSP00000487519
,
ENSP00000445635
,
ENSP00000478927
,
ENSP00000431574
,
ENST00000615667
,
ENST00000629586
,
ENST00000524575
,
ENST00000537274
,
ENST00000282441
,
ENST00000531439
,
ENSG00000137693
,
ENST00000345877
,
ENST00000526343
,
ENSP00000435602
,
ENSP00000331023
,
ENSP00000282441
PRO
P46937
Pharos - Targets
P46937
Orphanet
22672
PDB
3KYS
,
6HIK
,
6GE5
,
2LTV
,
6G8I
,
6GE6
,
2LTW
,
6GEK
,
6G8Q
,
5YDY
,
6GEI
,
2LAY
,
6GE3
,
1K9Q
,
1K5R
,
3MHR
,
6GEG
,
6GE4
,
5OAQ
,
1K9R
,
6GEE
,
7O07
,
2LAW
,
6G8L
,
6GEC
,
6G8P
,
8C2F
,
2LAX
,
5YDX
,
6Q2X
,
4RE1
,
1JMQ
,
4REX
,
6G6X
,
6G8J
,
8A8R
,
6HIL
,
6G8K
,
8A8Q
Interactors (52)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P28347 TEAD1
1
TEAD1 [nucleoplasm]
(R-HSA-2032774)
0.94
11
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.908
10
UniProt:P27348 YWHAQ
1
YWHAQ [cytosol]
(R-HSA-1445116)
0.906
9
UniProt:Q15561 TEAD4
1
TEAD4 [nucleoplasm]
(R-HSA-2032780)
0.897
12
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.894
11
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.894
9
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.882
11
UniProt:P35222 CTNNB1
20
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
pT41,S45-CTNNB1 S37A [cytosol]
(R-HSA-4839619)
pT41,S45-CTNNB1 S37Y [cytosol]
(R-HSA-9663978)
pT41,S45-CTNNB1 S37C [cytosol]
(R-HSA-4839617)
pS37,T41,S45-CTNNB1 S33A [cytosol]
(R-HSA-9663976)
pS37,T41,S45-CTNNB1 S33T [cytosol]
(R-HSA-9663977)
pS37,T41,S45-CTNNB1 S33C [cytosol]
(R-HSA-4839630)
pS37,T41,S45-CTNNB1 S33F [cytosol]
(R-HSA-4839628)
pS37,T41,S45-CTNNB1 S33P [cytosol]
(R-HSA-4839626)
pS37,T41,S45-CTNNB1 S33Y [cytosol]
(R-HSA-4839625)
pS45-CTNNB1 T41N [cytosol]
(R-HSA-9663980)
pS45-CTNNB1 T41A [cytosol]
(R-HSA-4836868)
pS45-CTNNB1 T41I [cytosol]
(R-HSA-4839612)
0.881
14
UniProt:O95835 LATS1
2
LATS1 [cytosol]
(R-HSA-2028562)
p-S909,T1079-LATS1 [cytosol]
(R-HSA-2028551)
0.88
10
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.842
9
UniProt:Q15562 TEAD2
1
TEAD2 [nucleoplasm]
(R-HSA-2032763)
0.823
9
UniProt:Q9BZD6 TMG4
0.815
5
UniProt:Q15678 PTPN14
1
PTPN14 [nucleoplasm]
(R-HSA-9008917)
0.813
8
UniProt:Q15599 NHRF2
0.809
6
UniProt:Q4VCS5 AMOT
0.802
6
UniProt:Q969T9 WBP2
0.759
7
UniProt:O14745 NHRF1
0.753
9
UniProt:P97764 WBP1
0.74
13
UniProt:O15350 TP73
3
PolyUb-TP73 [cytosol]
(R-HSA-8957256)
TP73 [cytosol]
(R-HSA-8957239)
TP73 [nucleoplasm]
(R-HSA-6798094)
0.73
5
UniProt:O15105 SMAD7
2
SMAD7 [nucleoplasm]
(R-HSA-178197)
SMAD7 [cytosol]
(R-HSA-173478)
0.715
7
UniProt:Q99594 TEAD3
1
TEAD3 [nucleoplasm]
(R-HSA-2032767)
0.68
5
UniProt:O75970 MPDZ
0.671
5
UniProt:Q8IY63 AMOTL1
1
AMOTL1 [cytosol]
(R-HSA-2028603)
0.671
5
UniProt:Q9Y2J4 AMOTL2
1
AMOTL2 [cytosol]
(R-HSA-2028606)
0.671
5
UniProt:Q13625 TP53BP2
1
TP53BP2 [nucleoplasm]
(R-HSA-6799780)
0.671
5
UniProt:Q8N3R9 MPP5
2
MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-9689606)
MPP5 [plasma membrane]
(R-HSA-419969)
0.671
5
UniProt:Q9Y297 BTRC
2
BTRC [cytosol]
(R-HSA-174237)
BTRC [nucleoplasm]
(R-HSA-3361753)
0.659
3
UniProt:O14669 TMG2
0.658
5
UniProt:O15350-1 TP73
0.65
7
UniProt:Q92841 DDX17
2
DDX17 [nucleoplasm]
(R-HSA-3900090)
monoSUMO1-K50-DDX17 [nucleoplasm]
(R-HSA-3900104)
0.649
7
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.643
3
UniProt:Q96G27 WBP1
0.623
4
UniProt:Q9P2Y5 UVRAG
2
UVRAG [cytosol]
(R-HSA-5668884)
UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-9730510)
0.623
2
UniProt:Q96PN7 TREF1
0.623
2
UniProt:Q13625-2 TP53BP2
0.618
9
UniProt:Q9H3D4 TP63
1
TP63 [nucleoplasm]
(R-HSA-2997585)
0.609
2
UniProt:Q8NI35 PATJ
1
PATJ [plasma membrane]
(R-HSA-420011)
0.569
4
UniProt:Q13131 PRKAA1
3
p-T183-PRKAA1 [cytosol]
(R-HSA-380964)
PRKAA1 [cytosol]
(R-HSA-380935)
p-T183-PRKAA1 [nucleoplasm]
(R-HSA-2151206)
0.564
3
UniProt:Q99593 TBX5
1
TBX5 [nucleoplasm]
(R-HSA-2032786)
0.558
4
UniProt:Q15562-2 TEAD2
0.556
3
UniProt:Q02750 MAP2K1
20
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1 F53S [cytosol]
(R-HSA-9652034)
MAP2K1 D67N [cytosol]
(R-HSA-9652016)
MAP2K1 Q56P [cytosol]
(R-HSA-9652064)
MAP2K1 E203K [cytosol]
(R-HSA-9652023)
MAP2K1 V60E [cytosol]
(R-HSA-9652067)
MAP2K1 P124S [cytosol]
(R-HSA-9652062)
MAP2K1 Y130C [cytosol]
(R-HSA-9652101)
MAP2K1 C121S [cytosol]
(R-HSA-9652013)
MAP2K1 G128V [cytosol]
(R-HSA-9652047)
MAP2K1 F53L [cytosol]
(R-HSA-9652031)
MAP2K1 K57N [cytosol]
(R-HSA-9652050)
MAP2K1 K57T [cytosol]
(R-HSA-9652052)
MAP2K1 F53V [cytosol]
(R-HSA-9652038)
MAP2K1 D67Y [cytosol]
(R-HSA-9652019)
MAP2K1 G128D [cytosol]
(R-HSA-9652043)
MAP2K1 P124L [cytosol]
(R-HSA-9652056)
MAP2K1 F53Y [cytosol]
(R-HSA-9652041)
MAP2K1 L42_K57del [cytosol]
(R-HSA-9652026)
0.556
3
UniProt:Q15797 SMAD1
4
Ub-SMAD1 [cytosol]
(R-HSA-6782768)
SMAD1 [cytosol]
(R-HSA-201468)
p-S463,S465-SMAD1 [cytosol]
(R-HSA-201464)
p-S463,S465-SMAD1 [nucleoplasm]
(R-HSA-201483)
0.544
3
UniProt:Q9NUP9 LIN7C
2
LIN7C [plasma membrane]
(R-HSA-5216165)
LIN7C [transport vesicle membrane]
(R-HSA-9610411)
0.527
3
UniProt:Q9Y4G8 RAPGEF2
1
RAPGEF2 [cytosol]
(R-HSA-5672599)
0.527
2
UniProt:Q96FJ2 DYNLL2
4
DYNLL2 [cytosol]
(R-HSA-2029024)
DYNLL2 [plasma membrane]
(R-HSA-140527)
DYNLL2 [cilium]
(R-HSA-5624865)
DYNLL2 [ciliary tip]
(R-HSA-5625337)
0.527
2
UniProt:A6NKD9 CC85C
0.527
3
UniProt:P35240 NF2
1
NF2 [plasma membrane]
(R-HSA-5669168)
0.527
2
UniProt:O14544 SOCS6
1
SOCS6 [cytosol]
(R-HSA-1469969)
0.524
2
UniProt:O35625 Axin1
8
Phospho Axin1 [cytosol]
(R-MMU-206175)
Axin1 [cytosol]
(R-MMU-4641133)
phospho-Axin1 [cytosol]
(R-MMU-3640864)
phospho-Axin1 [cytosol]
(R-MMU-3640841)
Axin1 [cytosol]
(R-MMU-205727)
Phospho (3 sites) Axin1 [cytosol]
(R-MMU-205737)
phospho-Axin1 [cytosol]
(R-MMU-206040)
Axin1 [cytosol]
(R-MMU-195249)
0.524
3
UniProt:O15169 AXIN1
11
AXIN1 L396M [cytosol]
(R-HSA-5251503)
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
p-T481,S486,S493-AXIN1 [cytosol]
(R-HSA-206040)
AXIN1 [cytosol]
(R-HSA-195249)
0.499
11
UniProt:P31947 SFN
1
SFN [cytosol]
(R-HSA-1445105)
0.471
2
IntAct:EBI-9253952 SUPER
0.462
3
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