Reactome | PMPCB [mitochondrial matrix]

PMPCB [mitochondrial matrix]

Stable Identifier

R-HSA-1299434

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Mitochondrial-processing peptidase subunit beta, MPPB_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75439 PMPCB

Gene Names

PMPCB, MPPB

Chain

transit peptide:1-43, chain:44-489

Reference Genes

BioGPS Gene:9512 PMPCB

COSMIC (genes):PMPCB PMPCB

CTD Gene:9512 PMPCB

dbSNP Gene:9512 PMPCB

ENSEMBL:ENSG00000105819 PMPCB

ENSEMBL_homo_sapiens_GENE:ENSG00000105819.15 PMPCB

HGNC:9119 PMPCB

KEGG Gene (Homo sapiens):9512 PMPCB

Monarch:9512 PMPCB

NCBI Gene:9512 PMPCB

OMIM:603131 PMPCB

UCSC:O75439 PMPCB

Reference Transcript

RefSeq:NM_004279.2 PMPCB

Other Identifiers

11732121_a_at

11732122_at

17049939

201682_PM_at

201682_at

244534_PM_at

244534_at

3017155

3017156

3017157

3017158

3017161

3017163

3017164

3017166

3017167

3017169

3017171

3017173

3017175

3017177

3017178

3017179

3017180

3017181

3017182

3017183

3017184

3017185

32167_at

8135235

83021_s_at

83022_r_at

9512

A_14_P137807

A_23_P134464

A_33_P3294162

GE61431

GE81374

GO:0003824

GO:0004222

GO:0005739

GO:0005743

GO:0005759

GO:0006508

GO:0006627

GO:0006851

GO:0006886

GO:0007005

GO:0008233

GO:0008237

GO:0016787

GO:0017087

GO:0043226

GO:0046872

GO:0051604

GO:0055085

GO:0140096

Hs.147877.0.A1_3p_at

PH_hs_0010853

TC07000672.hg

g4758733_3p_at

Participates

as a component of

PMPCB:Zn2+ [mitochondrial matrix] (Homo sapiens)

Inferred To

UQCR-C1 [mitochondrial matrix] (Drosophila melanogaster)

PMPCB [mitochondrial matrix] (Bos taurus)

PMPCB [mitochondrial matrix] (Caenorhabditis elegans)

PMPCB [mitochondrial matrix] (Canis familiaris)

PMPCB [mitochondrial matrix] (Gallus gallus)

PMPCB [mitochondrial matrix] (Mus musculus)

PMPCB [mitochondrial matrix] (Rattus norvegicus)

PMPCB [mitochondrial matrix] (Sus scrofa)

Cross References

RefSeq

NP_004270.2

OpenTargets

ENSG00000105819

HPA

ENSG00000105819-PMPCB

GeneCards

O75439

Ensembl

ENSG00000105819, ENST00000249269, ENSP00000249269

PRO

O75439

Pharos - Targets

O75439

Orphanet

28749

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.643	3
UniProt:Q9BQB4 SOST	1	SOST [extracellular region] (R-HSA-3769322)	0.527	3
UniProt:Q80H93 8b	1	8b [cytosol] (R-COV-9678168)	0.527	2
UniProt:Q9HC36 MRM3	1	RNMTL1 [mitochondrial matrix] (R-HSA-6793067)	0.527	2
UniProt:P01160 NPPA	5	NPPA(124-151) [extracellular region] (R-HSA-5578799) NPPA(1-151) [extracellular region] (R-HSA-976950) NPPA(1-25) [extracellular region] (R-HSA-5578791) NPPA(56-123) [extracellular region] (R-HSA-5578797) NPPA(26-55) [extracellular region] (R-HSA-5578794)	0.527	2

Cite Us!