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What is Reactome ?
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Table of Contents
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ERBIN [plasma membrane]
Stable Identifier
R-HSA-1358718
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ERBB2IP, LAP2
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Constitutive Signaling by Overexpressed ERBB2 (Homo sapiens)
ERBB2 binds TKIs (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 binds trastuzumab (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 homodimerization (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of ERBB2 homodimer (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Drug resistance in ERBB2 KD mutants (Homo sapiens)
Resistance of ERBB2 KD mutants to AEE788 (Homo sapiens)
Resistant ERBB2 KD mutants do not bind AEE788 (Homo sapiens)
ERBB2 KD mutants (AEE788 resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to afatinib (Homo sapiens)
ERBB2 T798M does not bind afatinib (Homo sapiens)
ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to lapatinib (Homo sapiens)
Resistant ERBB2 KD mutants do not bind lapatinib (Homo sapiens)
ERBB2 KD mutants (lapatinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to neratinib (Homo sapiens)
Resistant ERBB2 KD mutants do not bind neratinib (Homo sapiens)
ERBB2 KD mutants (neratinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to osimertinib (Homo sapiens)
ERBB2 KD mutants do not bind osimertinib (Homo sapiens)
ERBB2 KD mutants (osimertinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to sapitinib (Homo sapiens)
ERBB2 T862A does not bind sapitinib (Homo sapiens)
ERBB2 T862A:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to tesevatinib (Homo sapiens)
ERBB2 T733I does not bind tesevatinib (Homo sapiens)
ERBB2 T733I:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Resistance of ERBB2 KD mutants to trastuzumab (Homo sapiens)
Resistant ERBB2 KD mutants do not bind trastuzumab (Homo sapiens)
ERBB2 KD mutants (trastuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Drug resistance in ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD mutants do not bind pertuzumab (Homo sapiens)
ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Signaling by ERBB2 ECD mutants (Homo sapiens)
ERBB2 ECD mutants bind TKIs (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37:TKIs [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants bind trastuzumab (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37:trastuzumab [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants heterodimerize with EGFR (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37:TKIs [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37:trastuzumab [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Signaling by ERBB2 KD Mutants (Homo sapiens)
ERBB2 KD mutants bind TKIs (Homo sapiens)
ERBB2 KD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants bind trastuzumab (Homo sapiens)
ERBB2 KD mutants (trastuzumab sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants heterodimerize (Homo sapiens)
ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)
ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD mutants bind TKIs (Homo sapiens)
ERBB2 TMD/JMD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (TKI sensitive):TKI:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants bind pertuzumab (Homo sapiens)
ERBB2 R678Q:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants bind trastuzumab (Homo sapiens)
ERBB2 TMD/JMD mutants (trastuzumab):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (trastuzumab):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants hetrodimerize (Homo sapiens)
ERBB2 TMD/JMD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
Downregulation of ERBB2 signaling (Homo sapiens)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
CUL5 mediates ubiquitination of ERBB2 (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Drug-mediated inhibition of ERBB2 signaling (Homo sapiens)
ERBB2 binds TKIs (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 binds pertuzumab (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 binds trastuzumab (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG binds effectors at the plasma membrane (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96RT1 ERBIN
Gene Names
ERBIN, ERBB2IP, KIAA1225, LAP2
Chain
chain:1-1412
Reference Genes
BioGPS Gene:55914 ERBIN
COSMIC (genes):ERBIN ERBIN
CTD Gene:55914 ERBIN
dbSNP Gene:55914 ERBIN
ENSEMBL:ENSG00000112851 ERBIN
ENSEMBL:ENSG00000112851.16 ERBIN
HGNC:15842 ERBIN
KEGG Gene (Homo sapiens):55914 ERBIN
Monarch:55914 ERBIN
NCBI Gene:55914 ERBIN
OMIM:606944 ERBIN
UCSC:Q96RT1 ERBIN
Reference Transcript
RefSeq:NM_001006600.2 ERBIN
RefSeq:NM_001253698.1 ERBIN
RefSeq:NM_001253697.1 ERBIN
RefSeq:NM_001253701.1 ERBIN
RefSeq:NM_001253699.1 ERBIN
RefSeq:NM_018695.3 ERBIN
Other Identifiers
11734847_x_at
11734848_s_at
11751886_s_at
11751923_a_at
11758624_s_at
16985353
217941_PM_s_at
217941_s_at
222473_PM_s_at
222473_s_at
2812436
2812437
2812440
2812443
2812444
2812446
2812449
2812452
2812455
2812457
2812458
2812461
2812462
2812463
2812464
2812466
2812469
2812470
2812471
2812472
2812474
2812475
2812487
2812489
2812492
2812493
2812496
2812498
2812500
2812501
2812502
2812503
2812504
2812505
2812506
2812532
2812533
55914
60591_at
65956_at
8105681
A_14_P117084
A_23_P30175
GE53837
GE863600
GO:0002376
GO:0005102
GO:0005176
GO:0005198
GO:0005200
GO:0005515
GO:0005604
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0005886
GO:0006351
GO:0006355
GO:0006605
GO:0006886
GO:0007010
GO:0007155
GO:0007163
GO:0007165
GO:0007173
GO:0007229
GO:0009925
GO:0016020
GO:0016323
GO:0016607
GO:0023052
GO:0030054
GO:0030056
GO:0030312
GO:0031012
GO:0031594
GO:0031965
GO:0032088
GO:0032495
GO:0032496
GO:0043226
GO:0045104
GO:0045175
GO:0045197
GO:0070161
GO:0070433
GO:0071356
GO:0071638
GO:0098794
GO:0098978
GO:0099072
GO:0099572
HMNXSV003014801
HMNXSV003018102
HMNXSV003035735
Hs.8117.0.A1_3p_a_at
ILMN_1805024
ILMN_2352401
PH_hs_0000869
TC05000280.hg
g8923908_3p_a_at
Participates
as a component of
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Homo sapiens)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (trastuzumab):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (trastuzumab):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 R678Q:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (TKI sensitive):TKI:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (trastuzumab sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (lapatinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (AEE788 resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (trastuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (osimertinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants (neratinib resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 T733I:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 T862A:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
as an output of
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)
ERBB2 TMD/JMD mutants hetrodimerize (Homo sapiens)
ERBB2 KD mutants heterodimerize (Homo sapiens)
ERBB2 ECD mutants heterodimerize with EGFR (Homo sapiens)
ERBB2 homodimerization (Homo sapiens)
as a candidate of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
Inferred To
ERBIN [plasma membrane]
(Canis familiaris)
erbin [plasma membrane]
(Xenopus tropicalis)
Dmel\CG10307 [plasma membrane]
(Drosophila melanogaster)
Erbin [plasma membrane]
(Mus musculus)
Ghost homologue of ERBIN [plasma membrane]
(Bos taurus)
Ghost homologue of ERBIN [plasma membrane]
(Caenorhabditis elegans)
Ghost homologue of ERBIN [plasma membrane]
(Danio rerio)
Ghost homologue of ERBIN [plasma membrane]
(Gallus gallus)
Ghost homologue of ERBIN [plasma membrane]
(Rattus norvegicus)
Ghost homologue of ERBIN [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001240628.1
,
NP_061165.1
,
NP_001240630.1
,
NP_001240626.1
,
NP_001006600.1
,
NP_001240627.1
OpenTargets
ENSG00000112851
GeneCards
Q96RT1
HPA
ENSG00000112851-ERBIN
Ensembl
ENSP00000422766
,
ENSP00000426632
,
ENSP00000514079
,
ENSP00000514078
,
ENST00000380938
,
ENST00000508515
,
ENST00000506030
,
ENST00000511297
,
ENSP00000284037
,
ENSG00000112851
,
ENST00000284037
,
ENSP00000370325
,
ENST00000699000
,
ENST00000699001
,
ENSP00000370330
,
ENSP00000422015
,
ENST00000380943
PRO
Q96RT1
Pharos - Targets
Q96RT1
Orphanet
24517
PDB
6Q0U
,
6Q0N
,
6Q0M
,
1MFL
,
7LUL
,
1N7T
,
3CH8
,
2H3L
,
1MFG
,
2QBW
,
6UBH
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9HC29 NOD2
1
NOD2 [cytosol]
(R-HSA-168411)
0.664
5
UniProt:Q9UQ13 SHOC2
4
SHOC2 S2G [cytosol]
(R-HSA-9660457)
SHOC2 Q269_H270delinsHY [cytosol]
(R-HSA-9660464)
SHOC2 M173I [cytosol]
(R-HSA-9660486)
SHOC2 [cytosol]
(R-HSA-9658444)
0.623
4
UniProt:Q99569 PKP4
2
PKP4 [cornified envelope]
(R-HSA-8847721)
PKP4 [plasma membrane]
(R-HSA-6814401)
0.621
4
UniProt:P36873 PPP1CC
1
PPP1CC [cytosol]
(R-HSA-163443)
0.569
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
7
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