Reactome | ERBIN [plasma membrane]

ERBIN [plasma membrane]

Stable Identifier

R-HSA-1358718

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ERBB2IP, LAP2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96RT1 ERBIN

Gene Names

ERBIN, ERBB2IP, KIAA1225, LAP2

Chain

chain:1-1412

Reference Genes

BioGPS Gene:55914 ERBIN

COSMIC (genes):ERBIN ERBIN

CTD Gene:55914 ERBIN

dbSNP Gene:55914 ERBIN

ENSEMBL:ENSG00000112851 ERBIN

ENSEMBL:ENSG00000112851.16 ERBIN

HGNC:15842 ERBIN

KEGG Gene (Homo sapiens):55914 ERBIN

Monarch:55914 ERBIN

NCBI Gene:55914 ERBIN

OMIM:606944 ERBIN

UCSC:Q96RT1 ERBIN

Reference Transcript

Other Identifiers

11734847_x_at

11734848_s_at

11751886_s_at

11751923_a_at

11758624_s_at

16985353

217941_PM_s_at

217941_s_at

222473_PM_s_at

222473_s_at

2812436

2812437

2812440

2812443

2812444

2812446

2812449

2812452

2812455

2812457

2812458

2812461

2812462

2812463

2812464

2812466

2812469

2812470

2812471

2812472

2812474

2812475

2812487

2812489

2812492

2812493

2812496

2812498

2812500

2812501

2812502

2812503

2812504

2812505

2812506

2812532

2812533

55914

60591_at

65956_at

8105681

A_14_P117084

A_23_P30175

GE53837

GE863600

GO:0002376

GO:0005102

GO:0005176

GO:0005198

GO:0005200

GO:0005515

GO:0005604

GO:0005634

GO:0005635

GO:0005654

GO:0005737

GO:0005886

GO:0006351

GO:0006355

GO:0006605

GO:0006886

GO:0007010

GO:0007155

GO:0007163

GO:0007165

GO:0007173

GO:0007229

GO:0009925

GO:0016020

GO:0016323

GO:0016607

GO:0023052

GO:0030054

GO:0030056

GO:0030312

GO:0031012

GO:0031594

GO:0031965

GO:0032088

GO:0032495

GO:0032496

GO:0043226

GO:0045104

GO:0045175

GO:0045197

GO:0070161

GO:0070433

GO:0071356

GO:0071638

GO:0098794

GO:0098978

GO:0099072

GO:0099572

HMNXSV003014801

HMNXSV003018102

HMNXSV003035735

Hs.8117.0.A1_3p_a_at

ILMN_1805024

ILMN_2352401

PH_hs_0000869

TC05000280.hg

g8923908_3p_a_at

Participates

as a component of

as an output of

as a candidate of

Inferred To

ERBIN [plasma membrane] (Canis familiaris)

erbin [plasma membrane] (Xenopus tropicalis)

Dmel\CG10307 [plasma membrane] (Drosophila melanogaster)

Erbin [plasma membrane] (Mus musculus)

Ghost homologue of ERBIN [plasma membrane] (Bos taurus)

Ghost homologue of ERBIN [plasma membrane] (Caenorhabditis elegans)

Ghost homologue of ERBIN [plasma membrane] (Danio rerio)

Ghost homologue of ERBIN [plasma membrane] (Gallus gallus)

Ghost homologue of ERBIN [plasma membrane] (Rattus norvegicus)

Ghost homologue of ERBIN [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001240628.1, NP_061165.1, NP_001240630.1, NP_001240626.1, NP_001006600.1, NP_001240627.1

OpenTargets

ENSG00000112851

GeneCards

Q96RT1

HPA

ENSG00000112851-ERBIN

Ensembl

ENSP00000422766, ENSP00000426632, ENSP00000514079, ENSP00000514078, ENST00000380938, ENST00000508515, ENST00000506030, ENST00000511297, ENSP00000284037, ENSG00000112851, ENST00000284037, ENSP00000370325, ENST00000699000, ENST00000699001, ENSP00000370330, ENSP00000422015, ENST00000380943

PRO

Q96RT1

Pharos - Targets

Q96RT1

Orphanet

24517

PDB

6Q0U, 6Q0N, 6Q0M, 1MFL, 7LUL, 1N7T, 3CH8, 2H3L, 1MFG, 2QBW, 6UBH

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9HC29 NOD2	1	NOD2 [cytosol] (R-HSA-168411)	0.664	5
UniProt:Q9UQ13 SHOC2	4	SHOC2 S2G [cytosol] (R-HSA-9660457) SHOC2 Q269_H270delinsHY [cytosol] (R-HSA-9660464) SHOC2 M173I [cytosol] (R-HSA-9660486) SHOC2 [cytosol] (R-HSA-9658444)	0.623	4
UniProt:Q99569 PKP4	2	PKP4 [cornified envelope] (R-HSA-8847721) PKP4 [plasma membrane] (R-HSA-6814401)	0.621	4
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.569	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	7

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