Reactome | ERBIN [plasma membrane]

ERBIN [plasma membrane]

Stable Identifier

R-HSA-1358718

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ERBB2IP, LAP2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96RT1 ERBIN

Gene Names

ERBIN, ERBB2IP, KIAA1225, LAP2

Chain

chain:1-1412

Reference Genes

BioGPS Gene:55914 ERBIN

COSMIC (genes):ERBIN ERBIN

CTD Gene:55914 ERBIN

dbSNP Gene:55914 ERBIN

ENSEMBL:ENSG00000112851 ERBIN

HGNC:15842 ERBIN

KEGG:hsa:55914 ERBIN

Monarch:55914 ERBIN

NCBI Gene:55914 ERBIN

OMIM:606944 ERBIN

UCSC:Q96RT1 ERBIN

Reference Transcript

Participates

as a component of

as an output of

as a candidate of

Inferred To

ERBIN [plasma membrane] (Canis familiaris)

lrrA [plasma membrane] (Dictyostelium discoideum)

cyr1 [plasma membrane] (Schizosaccharomyces pombe)

Erbin [plasma membrane] (Mus musculus)

Ghost homologue of ERBIN [plasma membrane] (Bos taurus)

Ghost homologue of ERBIN [plasma membrane] (Caenorhabditis elegans)

Ghost homologue of ERBIN [plasma membrane] (Danio rerio)

Ghost homologue of ERBIN [plasma membrane] (Drosophila melanogaster)

Ghost homologue of ERBIN [plasma membrane] (Gallus gallus)

Ghost homologue of ERBIN [plasma membrane] (Rattus norvegicus)

Ghost homologue of ERBIN [plasma membrane] (Sus scrofa)

Cross References

RefSeq

XP_054208906.1, XP_047273340.1, NP_001240630.1, NP_001240626.1, NP_001006600.1, XP_047273336.1, XP_047273334.1, XP_047273339.1, XP_047273338.1, NP_001240628.1, NP_001240627.1, XP_054208905.1, XP_054208904.1, XP_054208902.1, NP_061165.1

OpenTargets

ENSG00000112851

ENSEMBL

ENSP00000514079, ENSG00000112851, ENSP00000514078, ENST00000380938, ENSP00000422766, ENST00000699000, ENST00000699001, ENST00000380943, ENST00000284037, ENSP00000426632, ENSP00000370325, ENST00000506030, ENSP00000422015, ENSP00000284037, ENST00000508515, ENST00000511297, ENSP00000370330

HPA

ENSG00000112851-ERBIN

GeneCards

ERBIN

PRO

Q96RT1

Pharos - Targets

Q96RT1

GlyGen

Q96RT1

Orphanet

ERBIN

PDB

3CH8, 6Q0U, 6Q0N, 2H3L, 6Q0M, 1N7T, 1MFL, 6UBH, 7LUL, 1MFG, 2QBW

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.745	7
UniProt:Q99569 PKP4	2	PKP4 [plasma membrane] (R-HSA-6814401) PKP4 [cornified envelope] (R-HSA-8847721)	0.73	5
UniProt:Q9HC29 NOD2	1	NOD2 [cytosol] (R-HSA-168411)	0.664	5
UniProt:Q9UQ13 SHOC2	4	SHOC2 [cytosol] (R-HSA-9658444) SHOC2 M173I [cytosol] (R-HSA-9660486) SHOC2 Q269_H270delinsHY [cytosol] (R-HSA-9660464) SHOC2 S2G [cytosol] (R-HSA-9660457)	0.623	4
UniProt:O00192 ARVC			0.609	2
UniProt:Q8NHY3 GA2L2			0.609	2
UniProt:K9N5R3 VEMP			0.609	2
UniProt:Q9UQB3 CTND2			0.609	2
UniProt:P25054 APC	20	APC R213* [cytosol] (R-HSA-9666924) APC C1410* [cytosol] (R-HSA-9666925) APC K1310* [cytosol] (R-HSA-9666926) APC R499* [cytosol] (R-HSA-9666927) APC R1450* [cytosol] (R-HSA-5251499) APC G1357* [cytosol] (R-HSA-9666940) APC L1488* [cytosol] (R-HSA-9666941) APC S1400* [cytosol] (R-HSA-9666942) APC S1346* [cytosol] (R-HSA-9666943) APC R405* [cytosol] (R-HSA-9666936) APC S1281* [cytosol] (R-HSA-9666937) APC E1573* [cytosol] (R-HSA-9666938) APC R805* [cytosol] (R-HSA-9666939) APC R1386* [cytosol] (R-HSA-9666932) APC S1327* [cytosol] (R-HSA-9666933) APC E1209* [cytosol] (R-HSA-9666934) APC Q1469* [cytosol] (R-HSA-9666935) APC R564* [cytosol] (R-HSA-9666928) APC E1536* [cytosol] (R-HSA-9666929) APC G1288* [cytosol] (R-HSA-9666930)	0.592	2
UniProt:P62136 PPP1CA	2	PPP1CA [cytosol] (R-HSA-163525) PPP1CA [nucleoplasm] (R-HSA-61995)	0.569	3
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-Y-CTNNB1 [cytosol] (R-HSA-8876940) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926)	0.554	2
UniProt:P20719 HXA5			0.527	2
UniProt:Q8WTR8 NET5			0.527	2
UniProt:P58166 INHBE	1	INHBE [extracellular region] (R-HSA-1449700)	0.527	2
UniProt:P03409 TAX			0.525	2
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.483	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.483	7
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.483	2

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