Reactome | CAV3 [plasma membrane]

CAV3 [plasma membrane]

Stable Identifier

R-HSA-1368135

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Caveolin-3, CAV3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9Y3A5 SBDS

Expand all

External Reference Information

External Reference

UniProt:P56539 CAV3

Gene Names

CAV3

Chain

chain:1-151

Reference Genes

BioGPS Gene:859 CAV3

COSMIC (genes):CAV3 CAV3

CTD Gene:859 CAV3

dbSNP Gene:859 CAV3

ENSEMBL:ENSG00000182533 CAV3

ENSEMBL_homo_sapiens_GENE:ENSG00000182533.7 CAV3

HGNC:1529 CAV3

KEGG Gene (Homo sapiens):859 CAV3

Monarch:859 CAV3

NCBI Gene:859 CAV3

OMIM:601253 CAV3

UCSC:P56539 CAV3

Reference Transcript

Other Identifiers

11728595_a_at

11741860_a_at

16937154

208204_PM_s_at

208204_s_at

2609471

2609472

2609473

2609477

2609478

2609479

41072_at

8077503

859

A_14_P120269

A_24_P251599

A_24_P319989

GE54374

GO:0000139

GO:0000165

GO:0001666

GO:0001778

GO:0002027

GO:0002931

GO:0003012

GO:0003013

GO:0003300

GO:0005246

GO:0005515

GO:0005783

GO:0005794

GO:0005886

GO:0005901

GO:0005925

GO:0006469

GO:0006629

GO:0006641

GO:0006816

GO:0006897

GO:0007009

GO:0007010

GO:0007015

GO:0007204

GO:0007517

GO:0007520

GO:0008016

GO:0008092

GO:0008104

GO:0008284

GO:0009986

GO:0010614

GO:0010831

GO:0014704

GO:0014819

GO:0014902

GO:0016010

GO:0016020

GO:0016192

GO:0017015

GO:0017080

GO:0019870

GO:0019899

GO:0023052

GO:0030018

GO:0030154

GO:0030163

GO:0030315

GO:0031116

GO:0031122

GO:0031579

GO:0031594

GO:0031982

GO:0032991

GO:0033292

GO:0035995

GO:0036211

GO:0038009

GO:0042060

GO:0042383

GO:0042391

GO:0042593

GO:0042632

GO:0043014

GO:0043226

GO:0043231

GO:0043407

GO:0043409

GO:0044325

GO:0044877

GO:0045121

GO:0045792

GO:0048856

GO:0050877

GO:0050998

GO:0051001

GO:0051394

GO:0051480

GO:0051647

GO:0051649

GO:0051896

GO:0051924

GO:0051926

GO:0055013

GO:0055065

GO:0055085

GO:0055117

GO:0060090

GO:0060299

GO:0060307

GO:0060347

GO:0060373

GO:0060762

GO:0061024

GO:0061052

GO:0065003

GO:0070836

GO:0071253

GO:0071417

GO:0072659

GO:0086005

GO:0090279

GO:0098772

GO:0098909

GO:1900744

GO:1900825

GO:1900826

GO:1901017

GO:1901019

GO:1901380

GO:2000009

GO:2000060

GO:2000649

GO:2001288

HMNXSV003017784

ILMN_1804980

ILMN_1810532

PH_hs_0005405

TC03000028.hg

g4580416_3p_a_at

Participates

as a component of

as an input of

DYSF, CAV3 and TRIM72 bind (Homo sapiens)

Inferred To

CAV3 [plasma membrane] (Bos taurus)

CAV3 [plasma membrane] (Canis familiaris)

CAV3 [plasma membrane] (Gallus gallus)

CAV3 [plasma membrane] (Sus scrofa)

cav-2 [plasma membrane] (Caenorhabditis elegans)

cav3 [plasma membrane] (Danio rerio)

cav3.1 [plasma membrane] (Xenopus tropicalis)

cav-1 [plasma membrane] (Caenorhabditis elegans)

Cav3 [plasma membrane] (Mus musculus)

Cav3 [plasma membrane] (Rattus norvegicus)

Homologues of CAV3 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001225.1, NP_203123.1

OpenTargets

ENSG00000182533

GeneCards

P56539

HPA

ENSG00000182533-CAV3

Ensembl

ENSP00000341940, ENSP00000380525, ENSG00000182533, ENST00000397368, ENST00000343849

PRO

P56539

Pharos - Targets

P56539

Orphanet

15403

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NZI2 PTRF	2	PTRF [nucleoplasm] (R-HSA-74981) CAVIN1 [plasma membrane] (R-HSA-9714278)	0.669	4
UniProt:Q96AL5 Q96AL5			0.556	3
UniProt:Q8N0V3 RBFA			0.556	3
UniProt:Q8NE08 Q8NE08			0.556	3
UniProt:Q9Y3A5 SBDS			0.527	2
UniProt:Q03135 CAV1	5	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009) CAV1 [early endosome membrane] (R-HSA-5368451)	0.527	2
UniProt:O75674 TM1L1			0.527	2
UniProt:Q9GZM5 YIPF3			0.527	2
UniProt:O94919 ENDOD1	2	ENDOD1 [extracellular region] (R-HSA-8862988) ENDOD1 [cytosol] (R-HSA-8862967)	0.527	2
UniProt:Q6SZW1 SARM1			0.527	2
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	2
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.527	2
UniProt:Q9UH99 SUN2	1	SUN2 [nuclear envelope] (R-HSA-912382)	0.527	2
UniProt:Q9H902 REEP1	1	REEP1 [endoplasmic reticulum membrane] (R-HSA-8939766)	0.527	2
UniProt:Q96BT3 CENPT	2	CENPT [nucleoplasm] (R-HSA-5633498) CENPT [cytosol] (R-HSA-375316)	0.527	2
UniProt:Q8N6S4 AN13C			0.527	2
UniProt:Q9NYZ3 GTSE1	4	GTSE1 [cytosol] (R-HSA-8852264) p-S435-GTSE1 [cytosol] (R-HSA-8852316) p-S435-GTSE1 [nucleoplasm] (R-HSA-8852332) p-T513,T526-GTSE1 [cytosol] (R-HSA-8852308)	0.527	2
UniProt:Q9UPU7 TBD2B			0.527	2
UniProt:Q9H6H4 REEP4			0.527	2
UniProt:Q9NYP9 MIS18A	1	MIS18A [nucleoplasm] (R-HSA-606299)	0.527	2
UniProt:Q96GE4 CEP95			0.527	2
UniProt:Q6P0N0 MIS18BP1	1	MIS18BP1 [nucleoplasm] (R-HSA-606300)	0.527	2
UniProt:O60493 SNX3	3	SNX3 [cytosol] (R-HSA-3247743) PolyUb-SNX3 [endosome membrane] (R-HSA-6782993) SNX3 [endosome membrane] (R-HSA-6782991)	0.527	2
UniProt:P56377 AP1S2	5	AP1S2 [cytoplasmic vesicle membrane] (R-HSA-351188) AP1S2 [Golgi membrane] (R-HSA-350812) AP1S2 [lysosomal membrane] (R-HSA-432711) AP1S2 [trans-Golgi network membrane] (R-HSA-2130394) AP1S2 [cytosol] (R-HSA-167695)	0.527	2
UniProt:P0DOE7 M	5	p-S95,T205-M [cytosol] (R-RSY-9831678) p-S95,T205-M [nucleoplasm] (R-RSY-9831706) M [nucleoplasm] (R-RSY-9831711) Nascent M [cytosol] (R-RSY-9828672) p-S95,T205-M [viral tegument] (R-RSY-9836531)	0.524	2

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