Inactivation of APC/C via direct inhibition of the APC/C complex

Stable Identifier
R-HSA-141430
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Inactivation of APC/C via direct inhibition of the APC/C complex
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In the direct inhibition model, the cytosolic Mitotic Checkpoint Complex, consisting of hBUBR1, hBUB3, Cdc20 and Mad2, directly inhibits APC/C by binding to it.
Literature References
Participants
Events
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Orthologous Events
Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)
Inactivation of APC/C via direct inhibition of the APC/C complex (Dictyostelium discoideum)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Gallus gallus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Saccharomyces cerevisiae)
Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)
Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)
Inactivation of APC/C via direct inhibition of the APC/C complex (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Yen, TJ  (2004-05-05)
Reviewed
Peters, JM  (2006-03-28)
Created
Yen, TJ  (2004-05-05)
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