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Cleaved Caspase-9 [cytosol]
Stable Identifier
R-HSA-141640
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)
Activation of caspase-3 (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
DCC:DIP13alpha:Caspase-9 [plasma membrane] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Caspase-9 binds DCC:DIP13alpha complex (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
DCC:DIP13alpha:Caspase-9 [plasma membrane] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Intrinsic Pathway for Apoptosis (Homo sapiens)
Apoptotic factor-mediated response (Homo sapiens)
Cytochrome c-mediated apoptotic response (Homo sapiens)
Activation of caspases through apoptosome-mediated cleavage (Homo sapiens)
Cleavage of Procaspase-3 by the apoptosome (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Cleavage of Procaspase-7 by the apoptosome (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Formation of apoptosome (Homo sapiens)
Cleavage of Procaspase‑9 to caspase‑9 (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Regulation of the apoptosome activity (Homo sapiens)
UACA binds apoptosome (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
UACA:apoptosome [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
XIAP binds CASP9 (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
XIAP:apoptosome [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
SMAC, XIAP-regulated apoptotic response (Homo sapiens)
SMAC (DIABLO) binds to IAPs (Homo sapiens)
SMAC binds XIAP within apoptosome (Homo sapiens)
APAF1:CYCS:CASP9:XIAP:DIABLO [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
XIAP:apoptosome [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes (Homo sapiens)
Dissociation of DIABLO:XIAP from the apoptosome complex (Homo sapiens)
APAF1:CYCS:CASP9:XIAP:DIABLO [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Apoptosome [cytosol] (Homo sapiens)
Cleaved Caspase-9 [cytosol] (Homo sapiens)
Participants
components
CASP9(331-416) [cytosol]
(Homo sapiens)
CASP9(?-315) [cytosol]
(Homo sapiens)
Participates
as a component of
Apoptosome [cytosol] (Homo sapiens)
DCC:DIP13alpha:Caspase-9 [plasma membrane] (Homo sapiens)
as an input of
Caspase-9 binds DCC:DIP13alpha complex (Homo sapiens)
Inferred To
Cleaved Caspase-9 [cytosol]
(Bos taurus)
Cleaved Caspase-9 [cytosol]
(Caenorhabditis elegans)
Cleaved Caspase-9 [cytosol]
(Canis familiaris)
Cleaved Caspase-9 [cytosol]
(Danio rerio)
Cleaved Caspase-9 [cytosol]
(Drosophila melanogaster)
Cleaved Caspase-9 [cytosol]
(Gallus gallus)
Cleaved Caspase-9 [cytosol]
(Mus musculus)
Cleaved Caspase-9 [cytosol]
(Rattus norvegicus)
Cleaved Caspase-9 [cytosol]
(Sus scrofa)
Cleaved Caspase-9 [cytosol]
(Xenopus tropicalis)
Cross References
ComplexPortal
CPX-991
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