SLC2A4 (GLUT4) vesicle fuses with the plasma membrane

Stable Identifier
R-HSA-1449574
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytoplasmic vesicle membrane, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
After docking at the membrane VAMP2 on the vesicle interacts with SYNTAXIN-4 and SNAP23 on the plasma membrane to catalyze fusion of the vesicle with the plasma membrane. STXBP3 (MUNC18C) bound to STX4 prevents fusion until STXBP3 is phosphorylated.
Participants
Input
Output
Participates
as an event of
Inferred From
Fusion of Glut4 Vesicle with the Plasma Membrane (Mus musculus)
Authored
May, B  (2011-07-13)
Reviewed
Klip, A  (2012-08-21)
Created
May, B  (2011-07-15)
Cite Us!