Reactome | ELN [extracellular region]

ELN [extracellular region]

Stable Identifier

R-HSA-1454880

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Tropoelastin, ELN_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q9UBX5 FBLN5

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External Reference Information

External Reference

UniProt:P15502 ELN

Gene Names

ELN

Chain

signal peptide:1-26, chain:27-786

Reference Genes

BioGPS Gene:2006 ELN

COSMIC (genes):ELN ELN

CTD Gene:2006 ELN

dbSNP Gene:2006 ELN

ENSEMBL:ENSG00000049540 ELN

HGNC:3327 ELN

KEGG:hsa:2006 ELN

Monarch:2006 ELN

NCBI Gene:2006 ELN

OMIM:130160 ELN

UCSC:P15502 ELN

Reference Transcript

Other Identifiers

2006

3008032

3008036

3008037

3008040

3008041

3008045

3008051

3008057

3008063

3008064

3008071

3008073

3008074

3008075

3008081

3008094

A_23_P215454

A_23_P215459

A_24_P186936

A_24_P186943

GE59419

GE80918

GO:0003013

GO:0003151

GO:0003180

GO:0005198

GO:0005201

GO:0005515

GO:0005576

GO:0007519

GO:0007585

GO:0008015

GO:0009887

GO:0030023

GO:0030198

GO:0030312

GO:0030833

GO:0031012

GO:0043149

GO:0048660

GO:0048856

GO:0050840

GO:0062023

GO:0071953

GO:0085029

HMNXSV003008215

ILMN_2385672

PH_hs_0028035

TC07000449.hg

Participates

as an input of

Tropoelastin forms aggregate globules (Homo sapiens)

as a component of

Tropoelastin aggregate [extracellular region] (Homo sapiens)

as a repeated unit of

Elastin [extracellular region] (Homo sapiens)

Other forms of this molecule

ELN(?-786) [extracellular region]

ELN(27-?) [extracellular region]

Inferred To

Ghost homologue of ELN [extracellular region] (Danio rerio)

Eln [extracellular region] (Mus musculus)

Eln [extracellular region] (Rattus norvegicus)

ELN [extracellular region] (Bos taurus)

ELN [extracellular region] (Canis familiaris)

ELN [extracellular region] (Gallus gallus)

ELN [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_001265868.1, NP_001075222.1, NP_001075221.1, NP_001265845.1, NP_001075223.1, NP_000492.2, NP_001265844.1, XP_047275927.1, NP_001075224.1, XP_054213425.1

OpenTargets

ENSG00000049540

ENSEMBL

ENSP00000391129, ENST00000320399, ENSP00000252034, ENSP00000369936, ENSP00000369926, ENSP00000369949, ENSG00000049540, ENST00000429192, ENST00000692049, ENSP00000369958, ENST00000252034, ENST00000380553, ENST00000380575, ENST00000357036, ENSP00000349540, ENST00000380584, ENST00000380576, ENST00000380562, ENSP00000313565, ENSP00000369950, ENSP00000510104

HPA

ENSG00000049540-ELN

GeneCards

ELN

PRO

P15502

Pharos - Targets

P15502

Orphanet

ELN

HMDB Protein

HMDBP01756

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95967 EFEMP2	1	EFEMP2 [extracellular region] (R-HSA-2161231)	0.645	5
UniProt:Q9UBX5 FBLN5	1	FBLN5 [extracellular region] (R-HSA-2161278)	0.611	3
UniProt:P28300 LOX	3	LOX(22-168) [extracellular region] (R-HSA-2022074) LOX(22-417) [extracellular region] (R-HSA-2022071) LOX [extracellular region] (R-HSA-2022085)	0.544	2
UniProt:P35555 FBN1	7	FBN1(45-2731) [extracellular region] (R-HSA-2159853) FBN1 [extracellular region] (R-HSA-265402) FBN1 [endoplasmic reticulum lumen] (R-HSA-8956726) p-FBN1 [endoplasmic reticulum lumen] (R-HSA-8956900) FBN1(45-?) [extracellular region] (R-HSA-2514785) FBN1(1-2731) [extracellular region] (R-HSA-2514817) FBN1(2732-2871) [extracellular region] (R-HSA-2159838)	0.524	3

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