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DEFA4(64-96) [azurophil granule lumen]
Stable Identifier
R-HSA-1470050
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
Defensin alpha 4, Neutrophil defensin 4, DEFA4, DEF4_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Defensins (Homo sapiens)
Alpha-defensins (Homo sapiens)
HNP1-4 are released into phagocytic vacuoles (Homo sapiens)
Defensins alpha 1-4 [azurophil granule lumen] (Homo sapiens)
DEFA4(64-96) [azurophil granule lumen] (Homo sapiens)
HNP1-4 are stored in primary neutrophil granules (Homo sapiens)
Defensins alpha 1-4 [azurophil granule lumen] (Homo sapiens)
DEFA4(64-96) [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12838 DEFA4
Gene Names
DEFA4, DEF4
Chain
signal peptide:1-19, propeptide:20-63, peptide:64-96, propeptide:-
Reference Genes
BioGPS Gene:1669 DEFA4
COSMIC (genes):DEFA4 DEFA4
CTD Gene:1669 DEFA4
dbSNP Gene:1669 DEFA4
ENSEMBL:ENSG00000164821 DEFA4
ENSEMBL_homo_sapiens_GENE:ENSG00000164821.5 DEFA4
ENSEMBL_homo_sapiens_GENE:ENSG00000285318.2 DEFA4
HGNC:2763 DEFA4
KEGG Gene (Homo sapiens):1669 DEFA4
Monarch:1669 DEFA4
NCBI Gene:1669 DEFA4
OMIM:601157 DEFA4
UCSC:P12838 DEFA4
Reference Transcript
RefSeq:NM_001925.2 DEFA4
Other Identifiers
11732546_at
1669
17074305
207269_PM_at
207269_at
3122723
3122724
3122725
3122726
3122727
34546_at
8149109
A_23_P326080
GE59919
GO:0002227
GO:0002376
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0006952
GO:0019730
GO:0019731
GO:0019732
GO:0030133
GO:0031410
GO:0031640
GO:0035580
GO:0042582
GO:0042742
GO:0042803
GO:0043226
GO:0045087
GO:0050829
GO:0050830
GO:0050832
GO:0051673
GO:0061844
GO:0071222
GO:0098542
HMNXSV003048490
ILMN_1753347
PH_hs_0000344
TC08000908.hg
X65977_at
g4503302_3p_at
Participates
as a candidate of
Defensins alpha 1-4 [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
DEFA4(64-96) [specific granule lumen]
DEFA4(64-96) [extracellular region]
DEFA4(20-63) [Golgi lumen]
DEFA4(64-96) [Golgi lumen]
DEFA4(20-96) [Golgi lumen]
DEFA4(1-96) [Golgi lumen]
Inferred To
Defa10 [azurophil granule lumen]
(Rattus norvegicus)
Np4 [azurophil granule lumen]
(Rattus norvegicus)
Defa25 [azurophil granule lumen]
(Mus musculus)
ENSRNOG00000064390 [azurophil granule lumen]
(Rattus norvegicus)
AY761185 [azurophil granule lumen]
(Mus musculus)
Defa36 [azurophil granule lumen]
(Mus musculus)
Defa9 [azurophil granule lumen]
(Rattus norvegicus)
Defa31 [azurophil granule lumen]
(Mus musculus)
Defa35 [azurophil granule lumen]
(Mus musculus)
Defa24 [azurophil granule lumen]
(Mus musculus)
Defa24 [azurophil granule lumen]
(Rattus norvegicus)
Defa29 [azurophil granule lumen]
(Mus musculus)
Defa42 [azurophil granule lumen]
(Mus musculus)
Defa5 [azurophil granule lumen]
(Mus musculus)
Defa20 [azurophil granule lumen]
(Mus musculus)
Defa8 [azurophil granule lumen]
(Rattus norvegicus)
Defa26 [azurophil granule lumen]
(Mus musculus)
Defa41 [azurophil granule lumen]
(Mus musculus)
Defa30 [azurophil granule lumen]
(Mus musculus)
Defa34 [azurophil granule lumen]
(Mus musculus)
Defa23 [azurophil granule lumen]
(Mus musculus)
Defal1 [azurophil granule lumen]
(Rattus norvegicus)
Homologues of DEFA4(64-96) [azurophil granule lumen]
(Mus musculus)
Homologues of DEFA4(64-96) [azurophil granule lumen]
(Rattus norvegicus)
Defa40 [azurophil granule lumen]
(Mus musculus)
DEFA4(64-96) [azurophil granule lumen]
(Mus musculus)
DEFA4(64-96) [azurophil granule lumen]
(Rattus norvegicus)
Defa3 [azurophil granule lumen]
(Mus musculus)
Defa38 [azurophil granule lumen]
(Mus musculus)
Defa [azurophil granule lumen]
(Rattus norvegicus)
Defa22 [azurophil granule lumen]
(Mus musculus)
Defa11 [azurophil granule lumen]
(Rattus norvegicus)
Defa17 [azurophil granule lumen]
(Mus musculus)
Defa2 [azurophil granule lumen]
(Mus musculus)
Defa39 [azurophil granule lumen]
(Mus musculus)
Defa28 [azurophil granule lumen]
(Mus musculus)
Defa21 [azurophil granule lumen]
(Mus musculus)
Defa6 [azurophil granule lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_001916.1
OpenTargets
ENSG00000164821
GeneCards
P12838
HPA
ENSG00000164821-DEFA4
Ensembl
ENST00000297435
,
ENST00000642522
,
ENSP00000297435
,
ENSG00000285318
,
ENSP00000493844
,
ENSG00000164821
PRO
P12838
Pharos - Targets
P12838
HMDB Protein
HMDBP10804
PDB
6DMQ
,
1ZMM
,
6DMM
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