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CLEC6A [plasma membrane]
Stable Identifier
R-HSA-1472857
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-type lectin domain family 6 member A, CLC6A_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
Dectin-2 family (Homo sapiens)
CLEC6A binds alpha-mannan in fungal cell walls (Homo sapiens)
CLEC6A:FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
CLEC6A:FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Homo sapiens)
pathogens:CLEC6A,CLEC4E:FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
PLCG2 translocates from cytosol to plasma membrane (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
SYK autophosphorylates (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
SYK binds to p-Y65,Y76-FCER1G (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Homo sapiens)
pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Homo sapiens)
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6EIG7 CLEC6A
Gene Names
CLEC6A, CLECSF10, DECTIN2
Chain
chain:1-209
Reference Genes
BioGPS Gene:93978 CLEC6A
COSMIC (genes):CLEC6A CLEC6A
CTD Gene:93978 CLEC6A
dbSNP Gene:93978 CLEC6A
ENSEMBL:ENSG00000205846 CLEC6A
ENSEMBL_homo_sapiens_GENE:ENSG00000205846.4 CLEC6A
HGNC:14556 CLEC6A
KEGG Gene (Homo sapiens):93978 CLEC6A
Monarch:93978 CLEC6A
NCBI Gene:93978 CLEC6A
OMIM:613579 CLEC6A
UCSC:Q6EIG7 CLEC6A
Reference Transcript
RefSeq:NM_001007033.1 CLEC6A
RefSeq:NM_001317999.1 CLEC6A
Other Identifiers
11738286_at
11738287_at
16747958
3403759
3403760
7953737
93978
A_33_P3295328
GO:0001819
GO:0001878
GO:0001879
GO:0002223
GO:0002250
GO:0002376
GO:0005509
GO:0005515
GO:0005537
GO:0005886
GO:0009897
GO:0016020
GO:0023052
GO:0030246
GO:0036211
GO:0038187
GO:0043123
GO:0043274
GO:0045087
GO:0046872
GO:0050731
GO:0050832
GO:0060089
GO:0061760
GO:0098542
GO:1902533
GO:2000318
HMNXSV003005326
ILMN_1742962
PH_hs_0039820
TC12000128.hg
Participates
as a component of
CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Homo sapiens)
CLEC6A:FCER1G dimer [plasma membrane] (Homo sapiens)
Inferred To
Ghost homologue of CLEC6A [plasma membrane]
(Rattus norvegicus)
CLEC6A [plasma membrane]
(Bos taurus)
illr4 [plasma membrane]
(Danio rerio)
Clec6a [plasma membrane]
(Mus musculus)
Cross References
RefSeq
NP_001304928.1
,
NP_001007034.1
Guide to Pharmacology - Targets
2928
OpenTargets
ENSG00000205846
GeneCards
Q6EIG7
HPA
ENSG00000205846-CLEC6A
Ensembl
ENSG00000205846
,
ENSP00000371505
,
ENST00000382073
PRO
Q6EIG7
Pharos - Targets
Q6EIG7
HMDB Protein
HMDBP12810
PDB
5VYB
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