Collagen type III degradation by MMP14

Stable Identifier
R-HSA-1474210
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The membrane-type MMP MMP14 (MT1-MMP) is a fibrillar collagenase able to degrade collagen types I, II and III (Ohuchi et al. 1997).
Literature References
PubMed ID Title Journal Year
8999957 Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

Fujii, Y, Okada, Y, Sato, H, Imai, K, Ohuchi, E, Seiki, M

J Biol Chem 1997
Participants
Participates
Catalyst Activity

metalloendopeptidase activity of MMP14,TMPRSS6 [plasma membrane]

Orthologous Events
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Created
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