DHAP is converted to 1-acyl GO3P by GNPAT

Stable Identifier
R-HSA-1483002
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Dihydroxyacetone phosphate (DHAP) is converted to 1-acyl glycerone 3-phosphate (GO3P) by the enzyme dihydroxyacetone phosphate acyltransferase (GNPAT) (de Vet et al. 1999, Ofman et al. 1994). This reaction step links Glycerolipid metabolism to Ether lipid metabolism.
Literature References
PubMed ID Title Journal Year
8186247 Purification of peroxisomal acyl-CoA: dihydroxyacetonephosphate acyltransferase from human placenta

Wanders, RJA, Ofman, R

Biochim Biophys Acta 1994
10553003 Ether lipid biosynthesis: alkyl-dihydroxyacetonephosphate synthase protein deficiency leads to reduced dihydroxyacetonephosphate acyltransferase activities

IJlst, L, Oostheim, W, van den Bosch, H, de Vet, EC, Dekker, C, Moser, HW

J Lipid Res 1999
Participants
Participates
Catalyst Activity

glycerone-phosphate O-acyltransferase activity of GNPAT [peroxisomal membrane]

Orthologous Events
Authored
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