Reactome | PETA and CTP are condensed to CDP-ETA by PCY2

PETA and CTP are condensed to CDP-ETA by PCY2

Stable Identifier

R-HSA-1483190

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol

ReviewStatus

5/5

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PETA and CTP are condensed to CDP-ETA by PCY2

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At the endoplasmic reticulum (ER) membrane, active membrane-bound ethanolamine-phosphate cytidylyltransferase (PCY2) dimer condenses phosphoethanolamine (PETA) and cytidine triphosphate (CTP) to produce CDP-ethanolamine (CDP-ETA) (Zhu et al. 2008, Nakashima et al. 1997).

Literature References

PubMed ID	Title	Journal	Year
9083101	Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant Hosaka, K, Nikawa, J, Nakashima, A	J Biol Chem	1997
18583706	Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1 Johnson, C, Bakovic, M, Zhu, L	J Lipid Res	2008