Reactome | PC:PITPNB is transported from the Golgi membrane to the ER membrane

PC:PITPNB is transported from the Golgi membrane to the ER membrane

Stable Identifier

R-HSA-1483211

Type

Reaction [transition]

Species

Homo sapiens

Compartment

Golgi membrane, endoplasmic reticulum membrane

ReviewStatus

5/5

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PC:PITPNB is transported from the Golgi membrane to the ER membrane

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The complex between phosphatidylcholine (PC) and phosphatidylinositol transfer protein beta isoform (PITPNB) transports from the Golgi membrane to the ER membrane (Carvou et al. 2010, Yoder et al. 2001, Shadan et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
18636990	Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells Ee, P, Murray-Rust, J, Li, M, Carvou, N, Shadan, S, Holic, R, Cockcroft, S	Traffic	2008
11104777	Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine Yarbrough, LR, Helmkamp GM, Jr, Oliver, RL, Tremblay, JM, Yoder, MD, Thomas, LM	J Biol Chem	2001
20332109	Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum Li, M, Skippen, A, Carvou, N, Holic, R, Cockcroft, S, Futter, C	J Cell Sci	2010