Glutathione is taken up by the bacterium

Stable Identifier
R-HSA-1500817
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Glutathione is taken up by the bacterium by an ABC transporter called the oligopeptide importer. OppA determines substrate specificity (Dasgupta et al. 2010).
Literature References
PubMed ID Title Journal Year
20808924 An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages

Das, AK, Mitra, D, Jackson, M, Sanyal, S, Basu, J, Gicquel, B, Sureka, K, Saha, B, Chakrabarti, P, Dasgupta, A, Kundu, M

PLoS One 2010
Participants
Participates
Catalyst Activity

peptide transmembrane transporter activity of Oligopeptide importer [plasma membrane]

Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Rhea
Authored
Reviewed
Created
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