Regulation of KIF20A (MKL2) by phosphorylation

Stable Identifier
R-HSA-156723
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Regulation of KIF20A (MKL2) by phosphorylation
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The polo-like kinase PLK1 phosphorylates KIF20A (also known as MKLP2 i.e. mitotic kinesin-like protein 2) on serine residue S528.

Literature References
PubMed ID Title Journal Year
12939256 Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis

Barr, FA, Nigg, EA, Kopajtich, R, Neef, R, Sutcliffe, J, Mayer, TU, Preisinger, C

J Cell Biol 2003
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as an event of
Catalyst Activity

protein serine/threonine kinase activity of p-T210-PLK1 [nucleoplasm]

Physical Entity
p-T210-PLK1 [nucleoplasm] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Regulation of KIF20A (MKL2) by phosphorylation (Bos taurus)
Regulation of KIF20A (MKL2) by phosphorylation (Canis familiaris)
Regulation of KIF20A (MKL2) by phosphorylation (Danio rerio)
Regulation of KIF20A (MKL2) by phosphorylation (Dictyostelium discoideum)
Regulation of KIF20A (MKL2) by phosphorylation (Drosophila melanogaster)
Regulation of KIF20A (MKL2) by phosphorylation (Mus musculus)
Regulation of KIF20A (MKL2) by phosphorylation (Rattus norvegicus)
Regulation of KIF20A (MKL2) by phosphorylation (Sus scrofa)
Regulation of KIF20A (MKL2) by phosphorylation (Xenopus tropicalis)
Created
Gillespie, ME  (2004-12-09)
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