Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Dissociation of L13a from the 60s ribosomal subunit
Stable Identifier
R-HSA-156826
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
Dissociation of L13a from the 60s ribosomal subunit (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The L13a subunit of the 60s ribosome is phosphorylated about 16 hours after INF gamma induction by an unknown kinase. At this time, L13a is also released from the 60s subunit (Mazumder et al.,2003). It is unclear, however, whether phosphorylation occurs before or after the release of L13a. Here, phosphorylation is shown as occurring after release.
Literature References
PubMed ID
Title
Journal
Year
14567916
Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control
Seshadri, V
,
Sampath, P
,
DiCorleto, PE
,
Maitra, RK
,
Fox, PL
,
Mazumder, B
Cell
2003
Participants
Input
60S ribosomal complex [cytosol]
(Homo sapiens)
Output
60s ribosomal complex lacking L13a subunit [cytosol]
(Homo sapiens)
RPL13A [cytosol]
(Homo sapiens)
Participates
as an event of
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
Orthologous Events
Dissociation of L13a from the 60s ribosomal subunit (Bos taurus)
Dissociation of L13a from the 60s ribosomal subunit (Caenorhabditis elegans)
Dissociation of L13a from the 60s ribosomal subunit (Canis familiaris)
Dissociation of L13a from the 60s ribosomal subunit (Danio rerio)
Dissociation of L13a from the 60s ribosomal subunit (Dictyostelium discoideum)
Dissociation of L13a from the 60s ribosomal subunit (Drosophila melanogaster)
Dissociation of L13a from the 60s ribosomal subunit (Mus musculus)
Dissociation of L13a from the 60s ribosomal subunit (Plasmodium falciparum)
Dissociation of L13a from the 60s ribosomal subunit (Rattus norvegicus)
Dissociation of L13a from the 60s ribosomal subunit (Saccharomyces cerevisiae)
Dissociation of L13a from the 60s ribosomal subunit (Schizosaccharomyces pombe)
Dissociation of L13a from the 60s ribosomal subunit (Sus scrofa)
Dissociation of L13a from the 60s ribosomal subunit (Xenopus tropicalis)
Authored
Matthews, L (2004-12-13)
Created
Gebauer, F (2004-12-20)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text