Reactome | EEF1D [cytosol]

EEF1D [cytosol]

Stable Identifier

R-HSA-156914

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-delta , Elongation factor 1-delta, eEF1B delta

Locations in the PathwayBrowser for interactor UniProt:P26641 EEF1G

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External Reference Information

External Reference

UniProt:P29692 EEF1D

Gene Names

EEF1D, EF1D

Chain

initiator methionine:, chain:2-281

Reference Genes

BioGPS Gene:1936 EEF1D

COSMIC (genes):EEF1D EEF1D

CTD Gene:1936 EEF1D

dbSNP Gene:1936 EEF1D

ENSEMBL:ENSG00000104529 EEF1D

ENSEMBL_homo_sapiens_GENE:ENSG00000104529.19 EEF1D

ENSEMBL_homo_sapiens_GENE:ENSG00000273594.4 EEF1D

HGNC:3211 EEF1D

KEGG Gene (Homo sapiens):1936 EEF1D

Monarch:1936 EEF1D

NCBI Gene:1936 EEF1D

OMIM:130592 EEF1D

UCSC:P29692 EEF1D

Reference Transcript

Other Identifiers

11730204_x_at

11741589_x_at

11754826_x_at

11759921_at

1936

203113_PM_s_at

203113_s_at

214394_PM_x_at

214394_x_at

3157597

3157598

3157599

3157600

3157603

3157605

3157606

3157613

3157614

3157615

3157616

3157617

3157619

3157623

3157624

3157627

3157635

3157636

3157637

3157640

3157641

3215032

3215040

3822577

3822579

3822580

3822582

3822584

41256_at

77361_g_at

8153449

8153457

89262_at

A_23_P31833

A_23_P31840

A_23_P389708

A_24_P926053

GE60364

GO:0000978

GO:0001650

GO:0002181

GO:0002182

GO:0003677

GO:0003746

GO:0005085

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005783

GO:0005829

GO:0005853

GO:0006351

GO:0006355

GO:0006412

GO:0006414

GO:0008135

GO:0031072

GO:0034605

GO:0043226

GO:0045182

GO:0045296

GO:0045944

GO:0071479

GO:0098772

GO:0140297

HMNXSV003038625

Hs.223241.1.A1_3p_x_at

ILMN_1703635

ILMN_1782543

ILMN_2408039

TC08001721.hg

Z21507_at

g4503478_3p_x_at

Participates

as an input of

Formation of eEF1B complex (Homo sapiens)

as a component of

eEF1B complex [cytosol] (Homo sapiens)

Inferred To

EFB1 [cytosol] (Saccharomyces cerevisiae)

tef5 [cytosol] (Schizosaccharomyces pombe)

EEF1D [cytosol] (Bos taurus)

EEF1D [cytosol] (Canis familiaris)

EEF1D [cytosol] (Gallus gallus)

EEF1D [cytosol] (Plasmodium falciparum)

EEF1D [cytosol] (Sus scrofa)

Eef1d [cytosol] (Mus musculus)

Eef1d [cytosol] (Rattus norvegicus)

Homologues of EEF1D [cytosol] (Plasmodium falciparum)

efa1B [cytosol] (Dictyostelium discoideum)

eEF1delta [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

XP_011515207.1, NP_001123527.1, XP_006716586.1, XP_006716588.1, XP_016868659.1, NP_001123529.1, NP_001276879.1, XP_006716587.1, XP_011515208.1, NP_001123525.2, XP_005250880.1, XP_006716585.1, NP_115754.3, NP_001182132.1, NP_001123528.1, NP_001304672.1, NP_001951.2, NP_001317575.1

OpenTargets

ENSG00000104529

GeneCards

P29692

HPA

ENSG00000104529-EEF1D

Ensembl

ENST00000619144, ENSP00000388261, ENSP00000431742, ENSP00000434448, ENSP00000488275, ENSP00000436542, ENSP00000431460, ENST00000632587, ENSP00000436507, ENST00000317198, ENST00000528610, ENSP00000488026, ENST00000419152, ENST00000530191, ENSP00000436933, ENSP00000317399, ENST00000632675, ENSP00000487680, ENSP00000431763, ENST00000526838, ENST00000632965, ENST00000533494, ENSP00000434872, ENSP00000483527, ENSG00000104529, ENSP00000433611, ENST00000529272, ENST00000618139, ENSP00000479653, ENST00000524624, ENST00000615698, ENSP00000480505, ENSP00000488672, ENST00000531218, ENST00000530445, ENSP00000378551, ENST00000631698, ENST00000614575, ENST00000395119, ENSP00000477608, ENSP00000435697, ENST00000620155, ENST00000615067, ENSP00000478340, ENSP00000484536, ENST00000534380, ENSP00000433412, ENSG00000273594, ENST00000534377, ENST00000442189, ENST00000529516, ENSP00000391944

PRO

P29692

Pharos - Targets

P29692

PDB

2MVM, 2MVN, 5JPO, 2N51

HMDB Protein

HMDBP08368

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26641 EEF1G	3	EEF1G [cytosol] (R-HSA-156925) EEF1G(1-343)-ALK(1106-1620) fusion [cytosol] (R-HSA-9710839) EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] (R-HSA-9710850)	0.813	8
UniProt:Q96DN0 ERP27			0.743	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.742	6
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.666	4
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.564	5
UniProt:P00441 SOD1	5	SOD1 [extracellular region] (R-HSA-350705) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) 2xHC-SOD1 [cytosol] (R-HSA-3299726) SOD1 [cytosol] (R-HSA-350697)	0.564	3
UniProt:P13693 TCTP			0.556	3
UniProt:P26641-2 EEF1G			0.556	3
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.553	2
UniProt:Q969K4 ABTB1			0.547	3
UniProt:P55197 AF10			0.527	2
UniProt:Q5T5U3 ARHGAP21	1	ARHGAP21 [cytosol] (R-HSA-8873918)	0.524	2
UniProt:O95352 ATG7	14	ATG7 [secretory granule lumen] (R-HSA-6801316) ATG7 [extracellular region] (R-HSA-6806451) ATG7 [ficolin-1-rich granule lumen] (R-HSA-6801293) ATG7(1-693)-BRAF(381-766) fusion [cytosol] (R-HSA-6802272) ATG7(1-693)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802517) CysO572-ATG7-MAP1LC3B [cytosol] (R-HSA-9820410) CysO572-ATG7-GARABAPL2 [cytosol] (R-HSA-9820413) CysO572-ATG7-GARABAP [cytosol] (R-HSA-9820417) CysO572-ATG7-GARABAPL1 [cytosol] (R-HSA-9820406) CysO572-ATG7-MAP1LC3C [cytosol] (R-HSA-9820407) CysO572-ATG7-MAP1LC3A [cytosol] (R-HSA-9820421) CysO572-ATG7-GARABAPL3 [cytosol] (R-HSA-9820420) CysO572-ATG7 [cytosol] (R-HSA-5683584) ATG7 [cytosol] (R-HSA-947867)	0.524	2
UniProt:Q08AD1 CAMP2			0.524	2
UniProt:Q67020 Q67020			0.508	2
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	5
UniProt:P05412 JUN	4	p-S63,S73-JUN [cytosol] (R-HSA-8868682) JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194)	0.462	4

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