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NOTCH2 [plasma membrane]
Stable Identifier
R-HSA-157005
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NTM-NEC 2 heterodimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Processing in Golgi (Homo sapiens)
Mature NOTCH heterodimer traffics to the plasma membrane (Homo sapiens)
NOTCH [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
DLL1 binds NOTCH2 (Homo sapiens)
DLL1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
DLL4 binds NOTCH2 (Homo sapiens)
DLL4:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
Gamma-secretase cleaves CNTN1:NOTCH2 to release NICD2 (Homo sapiens)
CNTN1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG1 binds NOTCH2 (Homo sapiens)
JAG1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG2 binds NOTCH2 (Homo sapiens)
JAG2:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 binds CNTN1 (Homo sapiens)
CNTN1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 binds MDK (Homo sapiens)
MDK:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2-ligand complex is cleaved to produce NEXT2 (Homo sapiens)
Ub-DLL/JAG:NOTCH2 [plasma membrane] (Homo sapiens)
DLL/JAG:NOTCH2 [plasma membrane] (Homo sapiens)
DLL1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
DLL4:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG2:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
Ubiquitination of DLL/JAG ligands upon binding to NOTCH2 (Homo sapiens)
DLL/JAG:NOTCH2 [plasma membrane] (Homo sapiens)
DLL1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
DLL4:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG2:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
Ub-DLL/JAG:NOTCH2 [plasma membrane] (Homo sapiens)
DLL/JAG:NOTCH2 [plasma membrane] (Homo sapiens)
DLL1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
DLL4:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG1:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
JAG2:NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH2 [plasma membrane] (Homo sapiens)
Participants
components
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region]
(Homo sapiens)
NOTCH2(1582-2471) [plasma membrane]
(Homo sapiens)
Participates
as a component of
MDK:NOTCH2 [plasma membrane] (Homo sapiens)
DLL4:NOTCH2 [plasma membrane] (Homo sapiens)
JAG2:NOTCH2 [plasma membrane] (Homo sapiens)
CNTN1:NOTCH2 [plasma membrane] (Homo sapiens)
as an input of
NOTCH2 binds MDK (Homo sapiens)
DLL4 binds NOTCH2 (Homo sapiens)
JAG2 binds NOTCH2 (Homo sapiens)
NOTCH2 binds CNTN1 (Homo sapiens)
as a member of
NOTCH2/Fringe-modified NOTCH2 [plasma membrane] (Homo sapiens)
NOTCH [plasma membrane] (Homo sapiens)
Inferred To
NOTCH2 [plasma membrane]
(Gallus gallus)
NOTCH2 [plasma membrane]
(Xenopus tropicalis)
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