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NOTCH3 [plasma membrane]
Stable Identifier
R-HSA-157048
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NTM-NEC 3 heterodimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Processing in Golgi (Homo sapiens)
Mature NOTCH heterodimer traffics to the plasma membrane (Homo sapiens)
NOTCH [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
NOTCH3 binds DLL1 (Homo sapiens)
DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 binds DLL4 (Homo sapiens)
DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 binds JAG1 (Homo sapiens)
JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 binds JAG2 (Homo sapiens)
JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3-ligand complex is cleaved to produce NEXT3 (Homo sapiens)
Ub-DLL/JAG:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Noncanonical activation of NOTCH3 (Homo sapiens)
Gamma-secretase cleaves YBX1:NOTCH3 (Homo sapiens)
YBX1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 binds YBX1 (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
YBX1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ubiquitination of DLL/JAG ligands upon binding to NOTCH3 (Homo sapiens)
DLL/JAG:NOTCH3 [plasma membrane] (Homo sapiens)
DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL/JAG:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
NOTCH3 [plasma membrane] (Homo sapiens)
Participants
components
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region]
(Homo sapiens)
NOTCH3(1572-2321) [plasma membrane]
(Homo sapiens)
Participates
as an input of
NOTCH3 binds YBX1 (Homo sapiens)
NOTCH3 binds JAG1 (Homo sapiens)
NOTCH3 binds DLL1 (Homo sapiens)
NOTCH3 binds DLL4 (Homo sapiens)
NOTCH3 binds JAG2 (Homo sapiens)
as a component of
YBX1:NOTCH3 [plasma membrane] (Homo sapiens)
JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG1:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL4:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-DLL1:NOTCH3 [plasma membrane] (Homo sapiens)
Ub-JAG2:NOTCH3 [plasma membrane] (Homo sapiens)
as a member of
NOTCH [plasma membrane] (Homo sapiens)
Inferred To
NOTCH3 [plasma membrane]
(Gallus gallus)
NOTCH3 [plasma membrane]
(Mus musculus)
NOTCH3 [plasma membrane]
(Rattus norvegicus)
NOTCH3 [plasma membrane]
(Xenopus tropicalis)
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