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About
What is Reactome ?
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Privacy Notice
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Digital Preservation
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RANBP2 [cytosol]
Stable Identifier
R-HSA-157703
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Nup358
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
Mitotic Spindle Checkpoint (Homo sapiens)
Amplification of signal from the kinetochores (Homo sapiens)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Homo sapiens)
MAD2 associates with the Mad1 kinetochore complex (Homo sapiens)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
MAD2 converted to an inhibitory state via interaction with Mad1 (Homo sapiens)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore:Mad1:MAD2* Complex [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mad1 binds kinetochore (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Release of activated MAD2 from kinetochores (Homo sapiens)
Kinetochore:Mad1:MAD2* Complex [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mad1:kinetochore complex [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
ESPL1 (Separase) cleaves centromeric cohesin (Homo sapiens)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Separation of sister chromatids (Homo sapiens)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mitotic Prometaphase (Homo sapiens)
EML4 and NUDC in mitotic spindle formation (Homo sapiens)
EML4 recruits NUDC to mitotic spindle (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore capture of astral microtubules (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Resolution of Sister Chromatid Cohesion (Homo sapiens)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Homo sapiens)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore assembly (Homo sapiens)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
PP2A-B56 dephosphorylates centromeric cohesin (Homo sapiens)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Phosphorylation of cohesin by PLK1 at centromeres (Homo sapiens)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Nuclear Envelope Breakdown (Homo sapiens)
Nuclear Pore Complex (NPC) Disassembly (Homo sapiens)
CDK1 phosphorylates NUP98 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
NEK6/NEK7 phosphorylates NUP98 (Homo sapiens)
Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Partially Disassembled NPC [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
HSF1 activation (Homo sapiens)
HSF1 trimer translocates to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Regulation of HSF1-mediated heat shock response (Homo sapiens)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Homo sapiens)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) (Homo sapiens)
Defective NPC does not transport GCK1:GKRP from cytosol to nucleoplasm (Homo sapiens)
Defective NPC [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
HCMV Nuclear Pore Docking (Homo sapiens)
HCMV Capsid:Nuclear Pore Complex [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of HCMV DNA Into the Nucleus (Homo sapiens)
HCMV Capsid:Nuclear Pore Complex [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
HCMV Late Events (Homo sapiens)
Translocation of SCP, Triplex (TRI) complex, CVC complex, and Accessory Proteins from the cytoplasm into the nucleous (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of MCP:pPR-AP:pAP Complex into the Nucleous (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Rev-mediated nuclear export of HIV RNA (Homo sapiens)
Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Translocation of nuclear RNA transport complex to cytoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
Interactions of Rev with host cellular proteins (Homo sapiens)
Nuclear import of Rev protein (Homo sapiens)
Rev:importin beta:B23 recruited to the nuclear pore (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
nucleoporin-associated Rev:Importin-beta:B23 complex [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Translocation of Rev:importin-beta:B23 to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
nucleoporin-associated Rev:Importin-beta:B23 complex [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Rev-mediated nuclear export of HIV RNA (Homo sapiens)
Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Translocation of nuclear RNA transport complex to cytoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Interactions of Vpr with host cellular proteins (Homo sapiens)
Vpr-mediated nuclear import of PICs (Homo sapiens)
Vpr binds nucleoporins (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
PIC anchored to the NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Influenza Infection (Homo sapiens)
Export of Viral Ribonucleoproteins from Nucleus (Homo sapiens)
NEP/NS2 Interacts with the Cellular Export Machinery (Homo sapiens)
vRNP Export through the nuclear pore (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral Messenger RNA Synthesis (Homo sapiens)
Export of Spliced Viral mRNA (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Viral mRNA Export (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
NS1 Mediated Effects on Host Pathways (Homo sapiens)
Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Docking and transport of the RNP:Karyopherin complex through the nuclear pore (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
Dimerized phospho-IRF3, IRF7 is transported to the nucleus (Homo sapiens)
6:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SARS-CoV-2 6 binds NUP98:RAE1 within NPC (Homo sapiens)
6:NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
Transcriptional regulation by small RNAs (Homo sapiens)
Importin-8 imports AGO2:miRNA into the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Translocation of ISGF3 complex to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Translocation of p-STAT1:p-STAT1 dimer to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Interleukin-17 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Homo sapiens)
NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Homo sapiens)
Beta-catenin migrates to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
STING mediated induction of host immune responses (Homo sapiens)
IRF3-mediated induction of type I IFN (Homo sapiens)
Dimerized phospho-IRF3 migrates to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
IRF3 mediated activation of type 1 IFN (Homo sapiens)
Dimerized phospho-IRF3 migrates to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RIP-mediated NFkB activation via ZBP1 (Homo sapiens)
NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF6 mediated NF-kB activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated MAPK activation (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TICAM1-dependent activation of IRF3/IRF7 (Homo sapiens)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Homo sapiens)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Homo sapiens)
NPC transports GCK1:GKRP from cytosol to nucleoplasm (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Metabolism of non-coding RNA (Homo sapiens)
snRNP Assembly (Homo sapiens)
Nuclear export of snRNA transcripts (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
snRNP nuclear import and release (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the export-competent mRNP complex through the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
mRNP complex dissociates from cytosolic face of NPC (Homo sapiens)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of Mature mRNAs Derived from Intronless Transcripts (Homo sapiens)
Transport of Mature mRNA Derived from an Intronless Transcript (Homo sapiens)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the SLBP Dependant Mature mRNA (Homo sapiens)
Docking of Mature Replication Dependent Histone mRNA with the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the SLBP independent Mature mRNA (Homo sapiens)
Docking of Mature Histone mRNA complex:TAP at the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Release of the SLBP independent Histone mRNA from the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA processing in the nucleus (Homo sapiens)
tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of DNA damage response and repair proteins (Homo sapiens)
RANBP2 SUMOylates PML with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RANBP2 SUMOylates PML with SUMO2 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RANBP2 SUMOylates SP100 with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RANBP2 SUMOylates SP100 with SUMO2 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SUMOylation of DNA replication proteins (Homo sapiens)
RANBP2 SUMOylates TOP2A with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SUMOylation of RNA binding proteins (Homo sapiens)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SUMOylation of SUMOylation proteins (Homo sapiens)
RANBP2 SUMOylates RANBP2 with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RANBP2 SUMOylates RANBP2 with SUMO2 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SUMOylation of chromatin organization proteins (Homo sapiens)
RANBP2 SUMOylates HDAC4 with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
RANBP2 SUMOylates HDAC4 with SUMO2,3 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
SUMOylation of ubiquitinylation proteins (Homo sapiens)
RANBP2 SUMOylates MDM2 with SUMO1 (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Formins (Homo sapiens)
AURKB phosphorylates DIAPH2-2 at kinetochores (Homo sapiens)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
Microtubule-bound kinetochore [cytosol] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
RANBP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49792 RANBP2
Gene Names
RANBP2, NUP358
Chain
chain:1-3224
Reference Genes
BioGPS Gene:5903 RANBP2
COSMIC (genes):RANBP2 RANBP2
CTD Gene:5903 RANBP2
dbSNP Gene:5903 RANBP2
ENSEMBL:ENSG00000153201 RANBP2
ENSEMBL_homo_sapiens_GENE:ENSG00000153201.17 RANBP2
HGNC:9848 RANBP2
KEGG Gene (Homo sapiens):5903 RANBP2
Monarch:5903 RANBP2
NCBI Gene:5903 RANBP2
OMIM:601181 RANBP2
UCSC:P49792 RANBP2
Reference Transcript
RefSeq:NM_006267.4 RANBP2
Other Identifiers
11722814_s_at
11722815_at
11722816_at
11754283_s_at
11758005_s_at
16884126
201711_PM_x_at
201711_x_at
201712_PM_s_at
201712_s_at
201713_PM_s_at
201713_s_at
226922_PM_at
226922_at
2492220
2492221
2492223
2492290
2492297
2492302
2492303
2492304
2492305
2492307
2492308
2492310
2492312
2492313
2492315
2492316
2492317
2498744
2498745
2498746
2498747
2498748
2498750
2498751
2498752
2498753
2498755
2498757
2498758
2498759
2498763
2498764
2498765
2499126
2499159
2499160
2499162
2499163
2499164
2499165
2499166
2499167
2499169
2499170
2499171
2499173
2499175
2499177
2499178
2499179
2499180
2499181
2499182
2499183
2499184
2499185
2499186
2499187
2499188
2499189
2499190
2499191
2499193
2499194
2499195
2499196
2499197
2499201
2499202
2499203
2499204
2499205
2499206
2499207
2499208
2499209
2499210
2499211
2499235
2499236
2499237
2499619
2499620
2499621
2499623
2499624
2499625
2499626
2499631
2499633
2499634
2499635
2499637
2499640
2499641
2499642
2499643
2499644
2499645
2499648
2499649
2499650
2563430
2563431
2563432
2563434
2563436
2563437
2563439
2563440
2563442
2563444
2563446
2563447
2563448
2563452
2563455
2563456
2563458
2569096
2569097
2569098
2569102
2569103
2569104
2569105
2569107
2569109
2569110
2569111
2569112
2569116
2569117
2569118
2569119
2569120
2570484
2570486
2570488
2570490
2570491
2570493
2570494
2570495
2570498
2570499
2570500
2570501
2570503
2570510
2570511
2570512
2570513
2570515
2570516
2570517
2570556
2570557
2570559
2570561
2570564
2570566
2570567
2570569
2570570
2570571
2570574
2570576
2570577
2570578
2570580
2570588
2570589
2570590
2570591
2570593
2570594
2570595
2571300
2571302
2571303
2571305
2571306
2571308
2571309
2571310
2571313
2571315
2571316
2571317
2571319
2571326
2571327
2571328
2571329
2571331
2571332
2571333
32788_at
51177_at
5903
8044161
8044263
8044304
8054414
8054532
8054557
8054676
A_14_P113906
A_23_P131664
A_24_P350890
A_33_P3272390
A_33_P3308740
D42063_at
GE61553
GE80234
GO:0000413
GO:0001975
GO:0003723
GO:0003755
GO:0003824
GO:0005096
GO:0005515
GO:0005634
GO:0005635
GO:0005642
GO:0005643
GO:0005654
GO:0005737
GO:0005829
GO:0005975
GO:0006111
GO:0006457
GO:0006607
GO:0006807
GO:0006886
GO:0006913
GO:0015031
GO:0016020
GO:0016740
GO:0016853
GO:0016925
GO:0019789
GO:0031267
GO:0031965
GO:0036211
GO:0042405
GO:0043170
GO:0043226
GO:0043231
GO:0044238
GO:0044614
GO:0044615
GO:0044877
GO:0046872
GO:0046907
GO:0051028
GO:0051168
GO:0051642
GO:0061665
GO:0098772
GO:0106068
GO:0140096
GO:1990723
HMNXSV003021186
HMNXSV003037067
Hs.199179.0.S1_3p_s_at
Hs.28248.0.A1_3p_at
ILMN_1654866
ILMN_2320574
PH_hs_0011701
TC02000668.hg
g6382078_3p_a_at
g924266_3p_a_at
Participates
as a component of
Defective NPC [nuclear envelope] (Homo sapiens)
Partially Disassembled NPC [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Kinetochore [cytosol] (Homo sapiens)
Other forms of this molecule
polySUMO2-K2652,K2725-RANBP2 [nuclear envelope]
monoSUMO1-K2592,K2650,K2723-RANBP2 [nuclear envelope]
RANBP2 [nuclear envelope]
RANBP2(1-867)-p-7Y-ALK(1058-1620) fusion [cytosol]
RANBP2(1-867)-ALK(1058-1620) fusion [cytosol]
Inferred To
Nup358 [cytosol]
(Drosophila melanogaster)
ranbp2 [cytosol]
(Xenopus tropicalis)
YRB1 [cytosol]
(Saccharomyces cerevisiae)
Homologues of RANBP2 [cytosol]
(Saccharomyces cerevisiae)
Homologues of RANBP2 [cytosol]
(Schizosaccharomyces pombe)
YRB2 [cytosol]
(Saccharomyces cerevisiae)
hba1 [cytosol]
(Schizosaccharomyces pombe)
ran-5 [cytosol]
(Caenorhabditis elegans)
RANBP2 [cytosol]
(Bos taurus)
RANBP2 [cytosol]
(Canis familiaris)
RANBP2 [cytosol]
(Gallus gallus)
RANBP2 [cytosol]
(Sus scrofa)
NUP2 [cytosol]
(Saccharomyces cerevisiae)
sbp1 [cytosol]
(Schizosaccharomyces pombe)
Ranbp2 [cytosol]
(Mus musculus)
Ranbp2 [cytosol]
(Rattus norvegicus)
nup61 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_006258.3
OpenTargets
ENSG00000153201
HPA
ENSG00000153201-RANBP2
GeneCards
P49792
Ensembl
ENSG00000153201
,
ENSP00000283195
,
ENST00000283195
PRO
P49792
Pharos - Targets
P49792
Orphanet
17981
HMDB Protein
HMDBP08534
PDB
5CLL
,
7MNU
,
1XKE
,
7MNV
,
4LQW
,
5CLQ
,
7MNW
,
2LAS
,
7MNX
,
7MNJ
,
7MNL
,
4I9Y
,
7MNK
,
7R5J
,
3UIO
,
7MNY
,
7R5K
,
1Z5S
,
7MNM
,
7MNZ
,
4GA0
,
3UIP
,
7MNO
,
7MNN
,
7MNP
,
7MNQ
,
1RRP
,
4L6E
,
3UIN
,
7MNR
,
7MNS
,
7MNT
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62826 RAN
2
RAN [nucleoplasm]
(R-HSA-165528)
RAN [cytosol]
(R-HSA-165540)
0.861
7
UniProt:P63279 UBE2I
9
monoSUMO1-K14-UBE2I [nucleoplasm]
(R-HSA-4085358)
UBE2I [nuclear envelope]
(R-HSA-4655408)
SUMO2-C93-UBE2I [cytosol]
(R-HSA-4656944)
SUMO3-C93-UBE2I [nucleoplasm]
(R-HSA-3730629)
UBE2I [cytosol]
(R-HSA-4655342)
SUMO1-C93-UBE2I [cytosol]
(R-HSA-4656909)
SUMO2-C93-UBE2I [nucleoplasm]
(R-HSA-3730619)
SUMO1-C93-UBE2I [nucleoplasm]
(R-HSA-3730617)
UBE2I [nucleoplasm]
(R-HSA-912481)
0.854
7
UniProt:P46060 RANGAP1
3
RANGAP1 [nuclear envelope]
(R-HSA-167661)
monoSUMO1-K524-RANGAP1 [nuclear envelope]
(R-HSA-3000416)
RANGAP1 [cytosol]
(R-HSA-376255)
0.713
5
UniProt:O60260 PARK2
4
polyUb-PARK2 [cytosol]
(R-HSA-5689094)
p-S9-PRKN [cytosol]
(R-HSA-9793481)
p-S65-PRKN [cytosol]
(R-HSA-9834954)
PRKN [cytosol]
(R-HSA-201579)
0.639
11
UniProt:Q921C5-1 BICD2
0.633
4
UniProt:P52292 KPNA2
2
KPNA2 [nucleoplasm]
(R-HSA-206045)
KPNA2 [cytosol]
(R-HSA-205976)
0.547
2
UniProt:Q9BPX7 CG025
0.544
3
UniProt:Q9UBU9 NXF1
2
NXF1 [cytosol]
(R-HSA-156481)
NXF1 [nucleoplasm]
(R-HSA-111690)
0.527
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P61769 B2M
11
B2M(21-119) [early endosome membrane]
(R-HSA-182298)
B2M(21-119) [specific granule lumen]
(R-HSA-6806144)
B2M(21-119) [extracellular region]
(R-HSA-1302721)
B2M(21-119) [tertiary granule lumen]
(R-HSA-6800179)
B2M(21-119) [phagocytic vesicle membrane]
(R-HSA-1236891)
B2M(21-119) [recycling endosome membrane]
(R-HSA-8863880)
B2M(21-119) [early endosome lumen]
(R-HSA-1236827)
B2M(21-119) [Golgi membrane]
(R-HSA-983403)
B2M(21-119) [ER to Golgi transport vesicle membrane]
(R-HSA-983378)
B2M(21-119) [endoplasmic reticulum lumen]
(R-HSA-983063)
B2M(21-119) [plasma membrane]
(R-HSA-167743)
0.527
4
UniProt:O14524 NEMP1
0.527
3
UniProt:Q14974 KPNB1
5
KPNB1 [specific granule lumen]
(R-HSA-6799646)
KPNB1 [extracellular region]
(R-HSA-6806306)
KPNB1 [ficolin-1-rich granule lumen]
(R-HSA-6800978)
KPNB1 [nucleoplasm]
(R-HSA-180714)
KPNB1 [cytosol]
(R-HSA-180733)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
6
UniProt:P04626 ERBB2
20
ERBB2 G309E [plasma membrane]
(R-HSA-9665342)
ERBB2 G309A [plasma membrane]
(R-HSA-9665349)
ERBB2 S310F [plasma membrane]
(R-HSA-9665350)
ERBB2 S310Y [plasma membrane]
(R-HSA-9665344)
p-6Y-ERBB2 G309A [plasma membrane]
(R-HSA-9665381)
p-6Y-ERBB2 G309E [plasma membrane]
(R-HSA-9665382)
p-6Y-ERBB2 S310F [plasma membrane]
(R-HSA-9665379)
p-6Y-ERBB2 S310Y [plasma membrane]
(R-HSA-9665385)
p-Y-ERBB2 L755P [plasma membrane]
(R-HSA-9654268)
p-Y-ERBB2 I767M [plasma membrane]
(R-HSA-9654303)
p-Y-ERBB2 T798I [plasma membrane]
(R-HSA-9654618)
p-Y-ERBB2 Y772_A775dup [plasma membrane]
(R-HSA-9665652)
p-Y-ERBB2 T862A [plasma membrane]
(R-HSA-9654695)
p-Y-ERBB2 T798M [plasma membrane]
(R-HSA-9654615)
p-Y-ERBB2 H878Y [plasma membrane]
(R-HSA-9654833)
p-Y-ERBB2 V777L [plasma membrane]
(R-HSA-9654401)
p-Y-ERBB2 L755S [plasma membrane]
(R-HSA-9654194)
p-Y-ERBB2 V777E [plasma membrane]
(R-HSA-9654397)
p-Y-ERBB2 V777M [plasma membrane]
(R-HSA-9654398)
p-Y-ERBB2 L755M [plasma membrane]
(R-HSA-9654191)
0.463
3
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