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NUP43 [nuclear envelope]
Stable Identifier
R-HSA-157739
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nuclear envelope
Synonyms
Nup43
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of DNA replication proteins (Homo sapiens)
RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Homo sapiens)
RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
NUP43 [nuclear envelope] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NFH3 NUP43
Gene Names
NUP43
Chain
chain:1-380
Reference Genes
BioGPS Gene:348995 NUP43
COSMIC (genes):NUP43 NUP43
CTD Gene:348995 NUP43
dbSNP Gene:348995 NUP43
ENSEMBL:ENSG00000120253 NUP43
HGNC:21182 NUP43
KEGG:hsa:348995 NUP43
Monarch:348995 NUP43
NCBI Gene:348995 NUP43
OMIM:608141 NUP43
UCSC:Q8NFH3 NUP43
Reference Transcript
RefSeq:NM_198887.2 NUP43
Other Identifiers
11731488_x_at
11731489_x_at
11731490_a_at
11746714_a_at
11748575_a_at
11750219_a_at
11750220_x_at
17024633
219007_PM_at
219007_at
238474_PM_at
238474_at
2979057
2979058
2979059
2979060
2979061
2979062
2979063
2979068
2979070
2979071
2979072
2979074
2979075
2979076
2979077
2979078
2979082
2979083
2979089
348995
53050_at
65406_at
8130129
A_23_P31055
A_24_P200761
A_33_P3273063
GE82891
GE87773
GO:0000775
GO:0000776
GO:0005515
GO:0005634
GO:0005635
GO:0005643
GO:0005654
GO:0005694
GO:0005829
GO:0006913
GO:0007059
GO:0015031
GO:0016607
GO:0031080
GO:0043226
GO:0051028
GO:0051301
HMNXSV003001802
HMNXSV003002271
Hs.152164.0.S1_3p_at
ILMN_1661432
ILMN_1762674
PH_hs_0003545
TC06002215.hg
g13375888_3p_at
Participates
as a component of
RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Other forms of this molecule
NUP43 [cytosol]
Inferred To
Nup43 [nuclear envelope]
(Drosophila melanogaster)
Nup43 [nuclear envelope]
(Mus musculus)
Nup43 [nuclear envelope]
(Rattus norvegicus)
nup43 [nuclear envelope]
(Xenopus tropicalis)
NUP43 [nuclear envelope]
(Bos taurus)
NUP43 [nuclear envelope]
(Gallus gallus)
NUP43 [nuclear envelope]
(Sus scrofa)
Cross References
RefSeq
NP_942590.1
ENSEMBL
ENSP00000342262
,
ENST00000340413
,
ENST00000367404
,
ENSP00000356374
OpenTargets
ENSG00000120253
HPA
ENSG00000120253-NUP43
PRO
Q8NFH3
Pharos - Targets
Q8NFH3
GlyGen
Q8NFH3
PDB
7R5K
,
7R5J
,
7PEQ
,
4I79
,
5A9Q
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96S44 TP53RK
1
TP53RK [nucleoplasm]
(R-HSA-6784489)
0.643
3
UniProt:P55735 SEC13
4
SEC13 [lysosomal membrane]
(R-HSA-9638246)
SEC13 [endoplasmic reticulum membrane]
(R-HSA-203994)
SEC13 [ER to Golgi transport vesicle membrane]
(R-HSA-204012)
SEC13 [cytosol]
(R-HSA-203981)
0.643
5
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:Q99497 PARK7
7
PolyUb-Misfolded PARK7 [lysosomal lumen]
(R-HSA-9659997)
PolyUb-Misfolded PARK7 [cytosol]
(R-HSA-9641128)
Ub-Misfolded PARK7 [cytosol]
(R-HSA-9641123)
Misfolded PARK7 [cytosol]
(R-HSA-9641100)
PolyUb-Misfolded PARK7 [late endosome lumen]
(R-HSA-9660005)
PARK7 [nucleoplasm]
(R-HSA-3900141)
monoSUMO1-K130-PARK7 [nucleoplasm]
(R-HSA-4085351)
0.556
3
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
3
UniProt:P06307 CCK
1
CCK [extracellular region]
(R-HSA-388539)
0.556
3
UniProt:P23025 XPA
1
XPA [nucleoplasm]
(R-HSA-67437)
0.527
3
UniProt:Q8WYP5 AHCTF1
1
AHCTF1 [cytosol]
(R-HSA-376244)
0.488
3
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