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PAX5 [nucleoplasm]
Stable Identifier
R-HSA-158583
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Pax-5 protein, B-cell-specific transcription factor, BSAP
Locations in the PathwayBrowser for interactor UniProt:Q9UJX0 OSGI1
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in BCR signaling (Homo sapiens)
RUNX1 binds PAX5 (BSAP) (Homo sapiens)
PAX5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02548 PAX5
Gene Names
PAX5
Chain
chain:1-391
Reference Genes
BioGPS Gene:5079 PAX5
COSMIC (genes):PAX5 PAX5
CTD Gene:5079 PAX5
dbSNP Gene:5079 PAX5
ENSEMBL:ENSG00000196092 PAX5
ENSEMBL_homo_sapiens_GENE:ENSG00000196092.14 PAX5
HGNC:8619 PAX5
KEGG Gene (Homo sapiens):5079 PAX5
Monarch:5079 PAX5
NCBI Gene:5079 PAX5
OMIM:167414 PAX5
UCSC:Q02548 PAX5
Reference Transcript
RefSeq:NM_001280556.1 PAX5
RefSeq:NM_001280548.1 PAX5
RefSeq:NM_001280550.1 PAX5
RefSeq:NM_001280547.1 PAX5
RefSeq:NM_001280553.1 PAX5
RefSeq:NM_001280555.1 PAX5
RefSeq:NM_016734.2 PAX5
RefSeq:NM_001280549.1 PAX5
RefSeq:NM_001280552.1 PAX5
RefSeq:NM_001280554.1 PAX5
Other Identifiers
11737891_a_at
11737892_at
11745656_a_at
11745657_s_at
11745658_x_at
11753723_s_at
11753864_x_at
11756041_x_at
11756044_x_at
11762870_a_at
17093973
206802_PM_at
206802_at
221969_PM_at
221969_at
3205292
3205294
3205295
3205296
3205297
3205298
3205311
3205322
3205323
3205341
3205353
3205357
3205358
3205359
3205370
3205371
34620_at
49496_at
5079
8161211
A_23_P71624
GE58175
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0007283
GO:0007399
GO:0021670
GO:0021987
GO:0022414
GO:0030154
GO:0030183
GO:0030534
GO:0035914
GO:0043226
GO:0045944
GO:0048701
GO:0048856
GO:0140110
HMNXSV003013761
Hs.22030.1.A1_3p_at
ILMN_1687052
M96944_at
PH_hs_0001921
TC09001072.hg
TC09002474.hg
g9951919_3p_at
g9951919_3p_x_at
Participates
as a component of
RUNX1:CBFB:PAX5 [nucleoplasm] (Homo sapiens)
as an input of
RUNX1 binds PAX5 (BSAP) (Homo sapiens)
Inferred To
Poxn [nucleoplasm]
(Drosophila melanogaster)
toe [nucleoplasm]
(Drosophila melanogaster)
eyg [nucleoplasm]
(Drosophila melanogaster)
Pax5 [nucleoplasm]
(Mus musculus)
Pax5 [nucleoplasm]
(Rattus norvegicus)
eyg-1 [nucleoplasm]
(Caenorhabditis elegans)
egl-38 [nucleoplasm]
(Caenorhabditis elegans)
pax-2 [nucleoplasm]
(Caenorhabditis elegans)
sv [nucleoplasm]
(Drosophila melanogaster)
Homologues of PAX5 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of PAX5 [nucleoplasm]
(Drosophila melanogaster)
PAX5 [nucleoplasm]
(Bos taurus)
PAX5 [nucleoplasm]
(Canis familiaris)
PAX5 [nucleoplasm]
(Sus scrofa)
Pax-5 [nucleoplasm]
(Gallus gallus)
Cross References
RefSeq
NP_001267479.1
,
NP_001267476.1
,
NP_001267484.1
,
NP_001267482.1
,
NP_001267478.1
,
NP_001267483.1
,
NP_057953.1
,
NP_001267485.1
,
NP_001267481.1
,
NP_001267477.1
OpenTargets
ENSG00000196092
HPA
ENSG00000196092-PAX5
GeneCards
Q02548
Ensembl
ENSP00000350844
,
ENSP00000412188
,
ENST00000446742
,
ENSP00000404687
,
ENSP00000367078
,
ENSP00000367071
,
ENSP00000367084
,
ENSP00000367083
,
ENST00000377847
,
ENST00000523493
,
ENST00000520281
,
ENSP00000431038
,
ENST00000377853
,
ENST00000377852
,
ENSG00000196092
,
ENST00000358127
,
ENSP00000430773
,
ENST00000414447
,
ENST00000377840
PRO
Q02548
Pharos - Targets
Q02548
Orphanet
22409
PDB
1MDM
,
1K78
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00526 CDK3
0.556
3
UniProt:Q6NT76 HMBX1
0.556
3
UniProt:Q9NX04 AIRIM
0.556
3
UniProt:Q86UE8 TLK2
0.556
3
UniProt:Q6ISB3 GRHL2
0.556
3
UniProt:Q96Q77 CIB3
0.556
3
UniProt:P68400 CSNK2A1
2
CSNK2A1 [nucleoplasm]
(R-HSA-6805057)
CSNK2A1 [cytosol]
(R-HSA-201713)
0.556
3
UniProt:Q9UJ78-2 Q9UJ782
0.556
3
UniProt:Q96PV4 PNMA5
0.556
3
UniProt:Q7KZS0 Q7KZS0
0.556
3
UniProt:Q86UW9 DTX2
1
DTX2 [cytosol]
(R-HSA-1604436)
0.556
3
UniProt:Q14CS0 UBX2B
0.556
3
UniProt:P45984 MAPK9
3
MAPK9 [cytosol]
(R-HSA-450355)
p-T183,Y185-MAPK9 [cytosol]
(R-HSA-450293)
p-T183,Y185-MAPK9 [nucleoplasm]
(R-HSA-450319)
0.556
3
UniProt:O75934 BCAS2
1
BCAS2 [nucleoplasm]
(R-HSA-5420902)
0.556
3
UniProt:O15347 HMGB3
0.556
3
UniProt:Q6P4E2 Q6P4E2
0.556
3
IntAct:EBI-23202138 CCSB ORF ID
0.556
3
UniProt:P61024 CKS1B
1
CKS1B [nucleoplasm]
(R-HSA-187533)
0.556
3
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:Q9UJX0 OSGI1
0.556
3
UniProt:P60410 KRTAP10-8
1
KRTAP10-8 [cytosol]
(R-HSA-6810301)
0.556
3
UniProt:Q99469 STAC
0.556
3
UniProt:Q17RB8 LONRF1
1
LONRF1 [cytosol]
(R-HSA-8850905)
0.556
3
UniProt:Q13952-2 NFYC
0.556
3
UniProt:Q5SW96 LDLRAP1
2
LDLRAP1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869097)
LDLRAP1 [plasma membrane]
(R-HSA-171143)
0.556
3
UniProt:Q9UDX3 S14L4
0.556
3
UniProt:Q9P2W3 GNG13
1
GNG13 [plasma membrane]
(R-HSA-164346)
0.556
3
UniProt:Q96IV0 NGLY1
1
NGLY1 [cytosol]
(R-HSA-8850591)
0.556
3
UniProt:Q9BYQ3 KRTAP9-3
1
KRTAP9-3 [cytosol]
(R-HSA-6809954)
0.556
3
UniProt:Q8TB03 CX038
0.556
3
UniProt:Q9UBE0 SAE1
1
SAE1 [nucleoplasm]
(R-HSA-947697)
0.556
3
UniProt:Q2WGJ6 KLH38
0.556
3
UniProt:P23142-4 FBLN1
0.556
3
UniProt:Q8WYK0 ACOT12
1
ACOT12 [cytosol]
(R-HSA-5690072)
0.556
3
UniProt:Q969S2 NEIL2
1
NEIL2 [nucleoplasm]
(R-HSA-5649650)
0.556
3
UniProt:P24863 CCNC
1
CCNC [nucleoplasm]
(R-HSA-212418)
0.556
3
UniProt:O94888 WIPF1
2
UBXN7 [cytosol]
(R-HSA-8956071)
ub-UBXN7 [cytosol]
(R-HSA-9755305)
0.556
3
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.556
3
UniProt:P43351 RAD52
3
monoSUMO1-K411,K412,K414-RAD52 [nucleoplasm]
(R-HSA-4568909)
RAD52 [nucleoplasm]
(R-HSA-62639)
p-Y104-RAD52 [nucleoplasm]
(R-HSA-5686588)
0.556
3
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