Phenol can form a sulfate conjugate

Stable Identifier
R-HSA-158849
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Phenol can form a sulfate conjugate
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'PAPS', and 1 molecule of 'Phenol' are present. At the end of this reaction, 1 molecule of 'Phenyl sulfate', and 1 molecule of 'PAP' are present.

This reaction takes place in the 'cytosol' and is mediated by the 'aryl sulfotransferase activity' of 'SULT1A1 homodimer'.
Literature References
PubMed ID Title Journal Year
  Casarett and Doull's Toxicology 5th Edn

Parkinson, A

  1995
9034160 Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes

Weinshilboum, RM, Wood, TC, Raftogianis, RB, Her, C, Otterness, DM, Aksoy, IA

FASEB J 1997
12372849 Sulfonation and molecular action

Strott, CA

Endocr Rev 2002
Participants
Input
Output
Participates
as an event of
Catalyst Activity

aryl sulfotransferase activity of SULT1A1 dimer [cytosol]

Physical Entity
SULT1A1 dimer [cytosol] (Homo sapiens)
Activity
aryl sulfotransferase activity (GO:0004062)
Orthologous Events
Phenol can form a sulfate conjugate (Bos taurus)
Phenol can form a sulfate conjugate (Canis familiaris)
Phenol can form a sulfate conjugate (Danio rerio)
Phenol can form a sulfate conjugate (Drosophila melanogaster)
Phenol can form a sulfate conjugate (Gallus gallus)
Phenol can form a sulfate conjugate (Mus musculus)
Phenol can form a sulfate conjugate (Rattus norvegicus)
Phenol can form a sulfate conjugate (Sus scrofa)
Phenol can form a sulfate conjugate (Xenopus tropicalis)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2005-02-10)
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