Reactome | GABPA [nucleoplasm]

GABPA [nucleoplasm]

Stable Identifier

R-HSA-1592206

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

NRF2 alpha subunit, GA-binding protein alpha chain, GABPA_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q06547 GABPB1

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External Reference Information

External Reference

UniProt:Q06546 GABPA

Gene Names

GABPA, E4TF1A

Chain

chain:1-454

Reference Genes

BioGPS Gene:2551 GABPA

COSMIC (genes):GABPA GABPA

CTD Gene:2551 GABPA

dbSNP Gene:2551 GABPA

ENSEMBL:ENSG00000154727 GABPA

HGNC:4071 GABPA

KEGG:hsa:2551 GABPA

Monarch:2551 GABPA

NCBI Gene:2551 GABPA

OMIM:600609 GABPA

UCSC:Q06546 GABPA

Reference Transcript

Other Identifiers

11722717_a_at

11755033_a_at

16921850

210188_PM_at

210188_at

227428_PM_at

227428_at

243498_PM_at

243498_at

2551

3004044

3004292

3004294

3004295

3004296

3004297

37245_at

3916577

3916578

3916579

3916580

3916581

3916582

3916583

3916584

3916585

3916586

3916587

3916588

3916589

3916590

3916591

3916592

3916593

3916594

3916595

3916597

3916599

3916600

3916601

3916602

3916603

3916605

3916606

3916607

3916611

3916612

3916613

3916614

3916615

62479_at

8068039

8133030

A_23_P166219

A_33_P3269588

GE58938

GE736980

GO:0000122

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0001701

GO:0001825

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0030154

GO:0043565

GO:0045653

GO:0045944

GO:0048856

GO:1990837

HMNXSV003023595

Hs.259290.0.A1_3p_at

Hs.5905.0.A1_3p_at

ILMN_1750029

ILMN_2175562

PH_hs_0040994

TC21000078.hg

U13044_at

g286026_3p_at

Participates

as an output of

Expression of GABPA (NRF2 alpha subunit) (Homo sapiens)

as an input of

Formation of NRF2 (Homo sapiens)

as a component of

NRF2 [nucleoplasm] (Homo sapiens)

Inferred To

Gabpa [nucleoplasm] (Mus musculus)

Gabpa [nucleoplasm] (Rattus norvegicus)

Ets97D [nucleoplasm] (Drosophila melanogaster)

gabpa [nucleoplasm] (Danio rerio)

gabpa [nucleoplasm] (Xenopus tropicalis)

GABPA [nucleoplasm] (Bos taurus)

GABPA [nucleoplasm] (Canis familiaris)

GABPA [nucleoplasm] (Gallus gallus)

GABPA [nucleoplasm] (Sus scrofa)

Ghost homologue of GABPA [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of GABPA [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of GABPA [nucleoplasm] (Plasmodium falciparum)

Cross References

RefSeq

XP_011527823.1, XP_054180392.1, XP_054180391.1, NP_001184226.1, NP_002031.2, XP_054180390.1, XP_016883802.1, XP_011527822.1, XP_047296693.1, XP_005260995.1, XP_054180396.1, XP_047296694.1, XP_047296695.1, XP_024307830.1, XP_054180395.1, XP_054180394.1, XP_054180393.1, XP_054180389.1, XP_054180397.1

OpenTargets

ENSG00000154727

ENSEMBL

ENST00000400075, ENSP00000382948, ENST00000354828, ENSP00000346886, ENSG00000154727

HPA

ENSG00000154727-GABPA

GeneCards

GABPA

PRO

Q06546

Pharos - Targets

Q06546

GlyGen

Q06546

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TAK5 GABP2			0.775	7
UniProt:Q06547 GABPB1			0.703	6
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.59	2
UniProt:Q5TFG8 ZC21B			0.556	3
UniProt:O75716 STK16			0.556	3
UniProt:P08047 SP1	1	SP1 [nucleoplasm] (R-HSA-1592223)	0.544	2
UniProt:Q02447 SP3	3	monoSUMO1-K551-SP3 [nucleoplasm] (R-HSA-3247472) polySUMO2-K551-SP3 [nucleoplasm] (R-HSA-6804456) SP3 [nucleoplasm] (R-HSA-2160951)	0.544	2
UniProt:O95619 YEATS4	1	YEATS4 [nucleoplasm] (R-HSA-3322940)	0.527	3
UniProt:Q96J77 TPD55			0.527	3
UniProt:P51610 HCFC1	2	HCFC1 [nucleoplasm] (R-HSA-1592209) K48polyUb,K63polyUb-HCFC1 [nucleoplasm] (R-HSA-5690821)	0.499	2

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