NRF1:p-PPARGC1A, NRF2 bind the TFB1M promoter

Stable Identifier
R-HSA-1592236
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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NRF1:p-PPARGC1A, NRF2 bind the TFB1M promoter
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PGC-1alpha (PPARGC1A) binds NRF1 and coactivates genes regulated by NRF1 (Gleyzer et al. 2005, Vercauteren et al. 2008, inferred from mouse in Wu et al. 1999).

Literature References
PubMed ID Title Journal Year
10412986 Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Spiegelman, BM, Cinti, S, Lowell, B, Wu, Z, Adelmant, G, Mootha, V, Andersson, U, Zhang, C, Scarpulla, RC, Troy, A, Puigserver, P

Cell 1999
15684387 Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators

Gleyzer, N, Scarpulla, RC, Vercauteren, K

Mol Cell Biol 2005
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Authored
May, B  (2011-08-20)
Reviewed
Lezza, AM  (2013-12-07)
Created
May, B  (2011-09-09)
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