Reactome | IP6K1 [cytosol]

IP6K1 [cytosol]

Stable Identifier

R-HSA-1604591

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

IHPK1, KIAA0263

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q92551 IP6K1

Gene Names

IP6K1, IHPK1, KIAA0263

Chain

chain:1-441

Reference Genes

COSMIC (genes):IP6K1 IP6K1

ENSEMBL:ENSG00000176095 IP6K1

HGNC:18360 IP6K1

UCSC:Q92551 IP6K1

Other Identifiers

11739160_a_at

11739161_a_at

11741385_a_at

11744100_a_at

16954157

16954175

212439_PM_at

212439_at

219920_PM_s_at

219920_s_at

2674655

2674656

2674657

2674658

2674659

2674660

2674661

2674662

2674663

2674664

2674665

2674666

2674667

2674668

2674669

2674670

2674671

2674672

2674674

2674675

2674676

2674677

2674679

2674680

2674685

2674691

2674694

2674695

2674696

2674697

2674710

2674711

2674712

2674714

2674716

36154_at

43399_s_at

44017_at

8087461

8087473

9807

A_23_P92202

A_24_P396105

A_33_P3320804

D87452_at

GE514363

GE57406

GE58522

GO:0000827

GO:0000828

GO:0000829

GO:0000832

GO:0001650

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006629

GO:0016301

GO:0016740

GO:0032958

GO:0043226

GO:0043647

GO:0046854

GO:0052723

GO:0052724

GO:0052836

GO:0052839

GO:0120163

GO:0180030

HMNXSV003014210

HMNXSV003018162

Hs.74579.0.S1_3p_at

ILMN_1656434

ILMN_1700231

ILMN_1720207

ILMN_1773645

ILMN_2392286

ILMN_2412927

PH_hs_0004254

PH_hs_0025685

PH_hs_0037194

TC03001415.hg

TC03001416.hg

TC03002904.hg

g11761620_3p_a_at

Participates

as a member of

IP6K1/3 [cytosol] (Homo sapiens)

Other forms of this molecule

IP6K1 [nucleoplasm]

Inferred To

ip6k1 [cytosol] (Danio rerio)

ip6k1 [cytosol] (Xenopus tropicalis)

I6KA [cytosol] (Dictyostelium discoideum)

Ip6k [cytosol] (Drosophila melanogaster)

IP6K1 [cytosol] (Bos taurus)

IP6K1 [cytosol] (Caenorhabditis elegans)

IP6K1 [cytosol] (Canis familiaris)

IP6K1 [cytosol] (Gallus gallus)

IP6K1 [cytosol] (Mus musculus)

IP6K1 [cytosol] (Plasmodium falciparum)

IP6K1 [cytosol] (Rattus norvegicus)

IP6K1 [cytosol] (Saccharomyces cerevisiae)

IP6K1 [cytosol] (Schizosaccharomyces pombe)

IP6K1 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000323780, ENSP00000482032, ENSP00000420762, ENST00000395238, ENSP00000378659, ENST00000460540, ENST00000321599, ENST00000613416

OpenTargets

ENSG00000176095

IntEnz

2.7.4.21

HPA

ENSG00000176095-IP6K1

PRO

Q92551

Pharos - Targets

Q92551

GlyGen

Q92551

HMDB Protein

HMDBP09443

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08670 VIM	11	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q01523 DEFA5	5	DEFA5(1-94) [Golgi lumen] (R-HSA-1467267) DEFA5(20-94) [Golgi lumen] (R-HSA-1467208) DEFA5(20-94) [secretory granule lumen] (R-HSA-1471358) DEFA5(20-94) [extracellular region] (R-HSA-1471344) DEFA5(?-94) [extracellular region] (R-HSA-1462017)	0.527	2
UniProt:P21802 FGFR2	20	FGFR2 IIIa TM [extracellular region] (R-HSA-8851703) FGFR2 [plasma membrane] (R-HSA-2023840) FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane] (R-HSA-8853137) FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane] (R-HSA-8853154) FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane] (R-HSA-8853123) FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane] (R-HSA-8853158) FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane] (R-HSA-8853150) FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane] (R-HSA-8853153) FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane] (R-HSA-8853139) FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane] (R-HSA-8853159) FGFR2 N549H [plasma membrane] (R-HSA-2033296) FGFR2 N549K [plasma membrane] (R-HSA-1637910) FGFR2 K660N [plasma membrane] (R-HSA-1637905) p-8Y-FGFR2 K660M [plasma membrane] (R-HSA-2033300) p-8Y-FGFR2 K660E [plasma membrane] (R-HSA-2033298) phosphorylated FGFR2 L764Hfs*4 [plasma membrane] (R-HSA-2071957) p-8Y-FGFR2 W290C [plasma membrane] (R-HSA-2029875) p-8Y-FGFR2 S267P [plasma membrane] (R-HSA-2029879) p-8Y-FGFR2 [plasma membrane] (R-HSA-2029874) p-8Y-FGFR2 N549K [plasma membrane] (R-HSA-2033306)	0.527	2

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