Reactome | ITPKB [cytosol]

ITPKB [cytosol]

Stable Identifier

R-HSA-1604605

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P27987 ITPKB

Gene Names

ITPKB

Chain

chain:1-946

Reference Genes

BioGPS Gene:3707 ITPKB

COSMIC (genes):ITPKB ITPKB

CTD Gene:3707 ITPKB

dbSNP Gene:3707 ITPKB

ENSEMBL:ENSG00000143772 ITPKB

HGNC:6179 ITPKB

KEGG:hsa:3707 ITPKB

Monarch:3707 ITPKB

NCBI Gene:3707 ITPKB

OMIM:147522 ITPKB

UCSC:P27987 ITPKB

Reference Transcript

Other Identifiers

11720738_at

11720739_s_at

11759966_at

1554306_3p_at

1554306_PM_at

1554306_at

16700058

203723_PM_at

203723_at

2458923

2458924

2458925

2458929

2458931

2458935

2458944

2458946

2458947

2458964

2458983

2458984

2458985

2458986

2458987

2458988

2458989

2458990

2458991

2458992

2458993

2458994

3707

37272_at

70726_at

7924760

A_23_P372255

A_24_P119545

GE59824

GO:0000165

GO:0000166

GO:0000828

GO:0002262

GO:0002376

GO:0005515

GO:0005516

GO:0005524

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0005856

GO:0006629

GO:0007165

GO:0007166

GO:0008440

GO:0016020

GO:0016301

GO:0016740

GO:0030154

GO:0030217

GO:0032957

GO:0032958

GO:0033030

GO:0035726

GO:0045059

GO:0045061

GO:0045638

GO:0046579

GO:0046638

GO:0046854

GO:0071277

HMNXSV003020332

HMNXSV003036154

HMNXSV003045167

ILMN_1700432

PH_hs_0004548

TC01003901.hg

X57206_at

g4504790_3p_at

Participates

as a component of

ITPKB:Ca2+:CALM1 [cytosol] (Homo sapiens)

as a member of

ITPKA/B/C [cytosol] (Homo sapiens)

Inferred To

ITPKB [cytosol] (Bos taurus)

ITPKB [cytosol] (Canis familiaris)

IP3K1 [cytosol] (Drosophila melanogaster)

lfe-2 [cytosol] (Caenorhabditis elegans)

Itpkb [cytosol] (Mus musculus)

Itpkb [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_002212.3, XP_005273177.1, NP_001375333.1

Guide to Pharmacology - Targets

1448

ENSEMBL

ENST00000366784, ENSP00000355748, ENST00000429204, ENSG00000143772, ENSP00000411152, ENSP00000272117, ENST00000272117

OpenTargets

ENSG00000143772

IntEnz

2.7.1.127

GeneCards

ITPKB

HPA

ENSG00000143772-ITPKB

PRO

P27987

Pharos - Targets

P27987

HMDB Protein

HMDBP00983

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.666	4
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.596	4
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.556	3
UniProt:Q8N9R8 SCAI	1	SCAI [nucleoplasm] (R-HSA-5666012)	0.556	3

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