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PLCZ1 [cytosol]
Stable Identifier
R-HSA-1604623
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Homo sapiens)
PLCbz [cytosol] (Homo sapiens)
PLCZ1:Ca2+ [cytosol] (Homo sapiens)
PLCZ1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86YW0 PLCZ1
Gene Names
PLCZ1
Chain
chain:1-608
Reference Genes
BioGPS Gene:89869 PLCZ1
COSMIC (genes):PLCZ1 PLCZ1
CTD Gene:89869 PLCZ1
dbSNP Gene:89869 PLCZ1
ENSEMBL:ENSG00000139151 PLCZ1
ENSEMBL_homo_sapiens_GENE:ENSG00000139151.16 PLCZ1
HGNC:19218 PLCZ1
KEGG Gene (Homo sapiens):89869 PLCZ1
Monarch:89869 PLCZ1
NCBI Gene:89869 PLCZ1
OMIM:608075 PLCZ1
UCSC:Q86YW0 PLCZ1
Reference Transcript
RefSeq:NM_001330769.1 PLCZ1
RefSeq:NM_001330774.1 PLCZ1
RefSeq:NM_033123.3 PLCZ1
Other Identifiers
11754905_a_at
16761997
231425_PM_at
231425_at
3446356
3446357
3446360
3446362
3446363
3446365
3446366
3446367
3446369
3446370
3446372
3446374
3446375
3446376
3446380
3446381
3446382
3446383
3446387
3446388
3446390
55530_at
7961604
89869
A_23_P105524
A_33_P3262301
GE62909
GO:0003824
GO:0004435
GO:0004629
GO:0005509
GO:0005546
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006629
GO:0006816
GO:0007165
GO:0007204
GO:0007338
GO:0007343
GO:0008081
GO:0008289
GO:0010314
GO:0016042
GO:0016787
GO:0022414
GO:0023052
GO:0032266
GO:0035556
GO:0043226
GO:0045120
GO:0048471
GO:0060470
GO:0061827
HMNXSV003028283
Hs.97542.0.A1_3p_at
ILMN_1757769
PH_hs_0005312
TC12001291.hg
Participates
as a component of
PLCZ1:Ca2+ [cytosol] (Homo sapiens)
Inferred To
plc-4 [cytosol]
(Caenorhabditis elegans)
plc-3 [cytosol]
(Caenorhabditis elegans)
PLCZ1 [cytosol]
(Bos taurus)
PLCZ1 [cytosol]
(Canis familiaris)
PLCZ1 [cytosol]
(Dictyostelium discoideum)
PLCZ1 [cytosol]
(Gallus gallus)
PLCZ1 [cytosol]
(Plasmodium falciparum)
PLCZ1 [cytosol]
(Saccharomyces cerevisiae)
PLCZ1 [cytosol]
(Schizosaccharomyces pombe)
PLCZ1 [cytosol]
(Sus scrofa)
Homologues of PLCZ1 [cytosol]
(Caenorhabditis elegans)
Plcz1 [cytosol]
(Mus musculus)
Plcz1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_149114.2
,
NP_001317703.1
,
NP_001317698.1
Guide to Pharmacology - Targets
1413
OpenTargets
ENSG00000139151
IntEnz
3.1.4.11
GeneCards
Q86YW0
HPA
ENSG00000139151-PLCZ1
Ensembl
ENSP00000445026
,
ENSP00000266505
,
ENST00000266505
,
ENSG00000139151
,
ENST00000539875
PRO
Q86YW0
Pharos - Targets
Q86YW0
Orphanet
24814
HMDB Protein
HMDBP07342
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