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MTMR6 [cytosol]
Stable Identifier
R-HSA-1604666
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
MTMR6 binds MTMR9 (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
MTMR6:MTMR9 [cytosol] (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Homo sapiens)
MTMR6:MTMR9,MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR6:MTMR9 [cytosol] (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Homo sapiens)
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Homo sapiens)
MTMR6:MTMR9,MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR6:MTMR9 [cytosol] (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Homo sapiens)
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Homo sapiens)
MTMR6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y217 MTMR6
Gene Names
MTMR6
Chain
chain:1-621
Reference Genes
BioGPS Gene:9107 MTMR6
COSMIC (genes):MTMR6 MTMR6
CTD Gene:9107 MTMR6
dbSNP Gene:9107 MTMR6
ENSEMBL:ENSG00000139505 MTMR6
HGNC:7453 MTMR6
KEGG:hsa:9107 MTMR6
Monarch:9107 MTMR6
NCBI Gene:9107 MTMR6
OMIM:603561 MTMR6
UCSC:Q9Y217 MTMR6
Reference Transcript
RefSeq:NM_004685.3 MTMR6
Other Identifiers
11723202_at
11723203_s_at
16777549
214429_PM_at
214429_at
228789_PM_at
228789_at
3506156
3506157
3506158
3506159
3506161
3506162
3506163
3506166
3506167
3506168
3506169
3506170
3506172
3506173
3506174
3506175
3506176
3506177
3506179
3506181
3506182
3506183
38035_at
7970655
9107
A_23_P25515
A_24_P419211
GO:0003824
GO:0004438
GO:0004722
GO:0004725
GO:0005515
GO:0005635
GO:0005737
GO:0005783
GO:0005793
GO:0005829
GO:0005886
GO:0006470
GO:0006629
GO:0006661
GO:0006897
GO:0016192
GO:0016311
GO:0016787
GO:0032587
GO:0042995
GO:0043226
GO:0046488
GO:0046856
GO:0048471
GO:0052629
GO:0106018
GO:0140096
HMNXSV003047776
Hs.79877.0.A1_3p_at
ILMN_1717180
TC13000498.hg
U47635_at
Participates
as an input of
MTMR6 binds MTMR9 (Homo sapiens)
as a component of
MTMR6:MTMR9 [cytosol] (Homo sapiens)
as a member of
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Homo sapiens)
Inferred To
YMR1 [cytosol]
(Saccharomyces cerevisiae)
MTMR6 [cytosol]
(Bos taurus)
MTMR6 [cytosol]
(Caenorhabditis elegans)
MTMR6 [cytosol]
(Canis familiaris)
MTMR6 [cytosol]
(Danio rerio)
MTMR6 [cytosol]
(Dictyostelium discoideum)
MTMR6 [cytosol]
(Drosophila melanogaster)
MTMR6 [cytosol]
(Gallus gallus)
MTMR6 [cytosol]
(Mus musculus)
MTMR6 [cytosol]
(Rattus norvegicus)
MTMR6 [cytosol]
(Schizosaccharomyces pombe)
MTMR6 [cytosol]
(Sus scrofa)
Homologues of MTMR6 [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_004676.3
ENSEMBL
ENSP00000371221
,
ENST00000381801
OpenTargets
ENSG00000139505
IntEnz
3.1.3.95
HPA
ENSG00000139505-MTMR6
PRO
Q9Y217
Pharos - Targets
Q9Y217
GlyGen
Q9Y217
HMDB Protein
HMDBP11838
PDB
2YF0
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QG7 MTMR9
1
MTMR9 [cytosol]
(R-HSA-6809239)
0.888
14
UniProt:Q9Y2J4-4 AMOTL2
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q5JR59 MTUS2
0.556
3
UniProt:Q13287 NMI
1
NMI [cytosol]
(R-HSA-9731022)
0.556
6
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