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MMP7(51-267) [extracellular region]
Stable Identifier
R-HSA-1604766
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
MMP7 intermediate form, Matrilysin-1, MMP7_HUMAN, MMP7
Locations in the PathwayBrowser for interactor UniProt:O75175 CNOT3
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Autocatalytic activation of MMP7 (Homo sapiens)
MMP7(51-267) [extracellular region] (Homo sapiens)
Initial activation of proMMP7 by trypsin (Homo sapiens)
MMP7(51-267) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09237 MMP7
Gene Names
MMP7, MPSL1, PUMP1
Chain
signal peptide:1-17, propeptide:18-94, chain:95-267
Reference Genes
BioGPS Gene:4316 MMP7
COSMIC (genes):MMP7 MMP7
CTD Gene:4316 MMP7
dbSNP Gene:4316 MMP7
ENSEMBL:ENSG00000137673 MMP7
HGNC:7174 MMP7
KEGG:hsa:4316 MMP7
Monarch:4316 MMP7
NCBI Gene:4316 MMP7
OMIM:178990 MMP7
UCSC:P09237 MMP7
Reference Transcript
RefSeq:NM_002423.4 MMP7
Other Identifiers
11744030_a_at
11744031_at
11756074_a_at
11761764_at
16743647
204259_PM_at
204259_at
3388674
3388675
3388676
3388677
3388678
3388679
3388680
3388681
3388682
3388683
3388684
3388685
3388686
4316
668_s_at
7951217
A_23_P52761
GE60350
GO:0002779
GO:0002780
GO:0003824
GO:0004175
GO:0004222
GO:0004252
GO:0005515
GO:0005576
GO:0005615
GO:0006508
GO:0006509
GO:0008233
GO:0008237
GO:0008270
GO:0009410
GO:0016787
GO:0022617
GO:0030198
GO:0030312
GO:0030335
GO:0030574
GO:0031012
GO:0031293
GO:0042127
GO:0042742
GO:0043226
GO:0046872
GO:0050829
GO:0050830
GO:0070062
GO:0098542
GO:0140096
HMNXSV003056491
ILMN_1685403
ILMN_2192072
L22524_s_at
PH_hs_0027041
TC11002228.hg
Participates
as an input of
Autocatalytic activation of MMP7 (Homo sapiens)
as an output of
Initial activation of proMMP7 by trypsin (Homo sapiens)
Other forms of this molecule
MMP7(18-267) [extracellular region]
MMP7(18-50) [extracellular region]
MMP7(51-94) [extracellular region]
MMP7(95-267) [extracellular region]
MMP7(18-94) [extracellular region]
Inferred To
MMP7(51-267) [extracellular region]
(Bos taurus)
MMP7(51-267) [extracellular region]
(Caenorhabditis elegans)
MMP7(51-267) [extracellular region]
(Canis familiaris)
MMP7(51-267) [extracellular region]
(Danio rerio)
MMP7(51-267) [extracellular region]
(Drosophila melanogaster)
MMP7(51-267) [extracellular region]
(Gallus gallus)
MMP7(51-267) [extracellular region]
(Mus musculus)
MMP7(51-267) [extracellular region]
(Rattus norvegicus)
MMP7(51-267) [extracellular region]
(Sus scrofa)
MMP7(51-267) [extracellular region]
(Xenopus tropicalis)
Homologues of MMP7(51-267) [extracellular region]
(Caenorhabditis elegans)
Homologues of MMP7(51-267) [extracellular region]
(Drosophila melanogaster)
Homologues of MMP7(51-267) [extracellular region]
(Gallus gallus)
Homologues of MMP7(51-267) [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_002414.1
ZINC - World Drugs
MMP7_HUMAN
Guide to Pharmacology - Targets
1631
OpenTargets
ENSG00000137673
ENSEMBL
ENST00000260227
,
ENSP00000260227
ZINC - Substances
MMP7_HUMAN
ZINC target
P09237
PRO
P09237
PDB
8JUF
,
8JUD
,
1MMQ
,
1MMR
,
2DDY
,
2MZE
,
7WXX
,
5UE2
,
5UE5
,
8JUG
,
2MZH
,
2Y6C
,
2MZI
,
2Y6D
,
8K4Z
,
1MMP
ZINC - Investigational
MMP7_HUMAN
HPA
ENSG00000137673-MMP7
Pharos - Targets
P09237
ZINC - Predictions - Purchasable
MMP7_HUMAN
HMDB Protein
HMDBP02928
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92600 RQCD1
2
RQCD1 [nucleoplasm]
(R-HSA-6810130)
RQCD1 [cytosol]
(R-HSA-430029)
0.527
3
UniProt:Q9NWU2 GID8
1
GID8 [cytosol]
(R-HSA-9861665)
0.527
2
UniProt:Q9C0C2 TNKS1BP1
1
TNKS1BP1 [cytosol]
(R-HSA-430011)
0.527
3
UniProt:Q9UFF9 CNOT8
1
CNOT8 [cytosol]
(R-HSA-429979)
0.527
2
UniProt:Q9UL63 MKLN1
1
Muskelin [cytosol]
(R-HSA-9861557)
0.527
2
UniProt:Q9UKZ1 CNOT11
1
CNOT11 [cytosol]
(R-HSA-429981)
0.527
3
UniProt:O75175 CNOT3
1
CNOT3 [cytosol]
(R-HSA-429872)
0.527
3
UniProt:Q9UIV1 CNOT7
1
CNOT7 [cytosol]
(R-HSA-429877)
0.527
3
UniProt:Q96LI5 CNOT6L
1
CNOT6L [cytosol]
(R-HSA-430027)
0.527
3
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.489
5
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