Reactome | p-PKMYT1 [nucleoplasm]

p-PKMYT1 [nucleoplasm]

Stable Identifier

R-HSA-162650

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

phospho-Myt1

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External Reference Information

External Reference

UniProt:Q99640 PKMYT1

Gene Names

PKMYT1, MYT1

Chain

chain:1-499

Reference Genes

COSMIC (genes):MYT1 PKMYT1

COSMIC (genes):PKMYT1 PKMYT1

dbSNP Gene:9088 PKMYT1

ENSEMBL:ENSG00000127564 PKMYT1

Participates

as an output of

Inactivation of Myt1 kinase (Homo sapiens)

Other forms of this molecule

PKMYT1 [cytosol]

PKMYT1 [nucleoplasm]

Inferred To

Homologues of p-PKMYT1 [nucleoplasm] (Dictyostelium discoideum)

Homologues of p-PKMYT1 [nucleoplasm] (Schizosaccharomyces pombe)

phospho-Pkmyt1 [nucleoplasm] (Rattus norvegicus)

phospho-p-PKMYT1 [nucleoplasm] (Bos taurus)

phospho-p-PKMYT1 [nucleoplasm] (Caenorhabditis elegans)

phospho-p-PKMYT1 [nucleoplasm] (Canis familiaris)

phospho-p-PKMYT1 [nucleoplasm] (Danio rerio)

phospho-p-PKMYT1 [nucleoplasm] (Dictyostelium discoideum)

phospho-p-PKMYT1 [nucleoplasm] (Drosophila melanogaster)

phospho-p-PKMYT1 [nucleoplasm] (Mus musculus)

phospho-p-PKMYT1 [nucleoplasm] (Saccharomyces cerevisiae)

phospho-p-PKMYT1 [nucleoplasm] (Schizosaccharomyces pombe)

phospho-p-PKMYT1 [nucleoplasm] (Sus scrofa)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06493 CDK1	11	p-T161-CDK1 [nucleoplasm] (R-HSA-170066) p-T14,Y15,T161-CDK1 [nucleoplasm] (R-HSA-170074) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T14,Y15,T161-CDK1 [cytosol] (R-HSA-170071) CDK1 [cytosol] (R-HSA-170075) CDK1 [nucleoplasm] (R-HSA-68889) p-T14-CDK1 [cytosol] (R-HSA-170064) p-T14-CDK1 [nucleoplasm] (R-HSA-170045) p-T14,T161-CDK1 [nucleoplasm] (R-HSA-170078) p-Y4-CDK1 [cytosol] (R-HSA-9836187) CDK1 [endoplasmic reticulum membrane] (R-HSA-264424)	0.893	9
UniProt:P14635 CCNB1	4	CCNB1 [nucleoplasm] (R-HSA-68901) p-4S-CCNB1 [cytosol] (R-HSA-170058) p-4S-CCNB1 [nucleoplasm] (R-HSA-170049) CCNB1 [cytosol] (R-HSA-157451)	0.867	8
UniProt:P33552 CKS2			0.725	4
UniProt:O95067 CCNB2	1	CCNB2 [cytosol] (R-HSA-68897)	0.725	5
UniProt:P20248 CCNA2	3	CCNA2 [nucleoplasm] (R-HSA-68905) CCNA2 [cytosol] (R-HSA-157444) PolyUb-CCNA2 [nucleoplasm] (R-HSA-6783099)	0.725	6
UniProt:P61024 CKS1B	1	CKS1B [nucleoplasm] (R-HSA-187533)	0.643	3
UniProt:P11440 Cdk1	11	phospho-p-T161-CDK1 [nucleoplasm] (R-MMU-170066) phospho-p-T14,Y15,T161-CDK1 [nucleoplasm] (R-MMU-170074) phospho-p-T161-CDK1 [cytosol] (R-MMU-157415) phospho-p-T14,Y15,T161-CDK1 [cytosol] (R-MMU-170071) CDK1 [cytosol] (R-MMU-170075) phospho-p-T14,T161-CDK1 [nucleoplasm] (R-MMU-170078) phospho-p-T14-CDK1 [nucleoplasm] (R-MMU-170045) phospho-p-T14-CDK1 [cytosol] (R-MMU-170064) Cdk1 [nucleoplasm] (R-MMU-1362302) phospho-p-Y4-CDK1 [cytosol] (R-MMU-9836187) CDK1 [endoplasmic reticulum membrane] (R-MMU-264424)	0.564	3
UniProt:O43291 SPINT2	1	SPINT2 [extracellular region] (R-HSA-6800233)	0.527	2
UniProt:P24394 IL4R	2	p-Y-IL4R [plasma membrane] (R-HSA-6786087) IL4R [plasma membrane] (R-HSA-449670)	0.527	2

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