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PLIN1 [lipid droplet]
Stable Identifier
R-HSA-163460
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lipid droplet
Synonyms
perilipin, PLIN
Locations in the PathwayBrowser for interactor UniProt:O14520 AQP7
Expand all
Developmental Biology (Homo sapiens)
Adipogenesis (Homo sapiens)
Transcriptional regulation of white adipocyte differentiation (Homo sapiens)
Expression of Perilipin (PLIN) (Homo sapiens)
PLIN1 [lipid droplet] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Triglyceride metabolism (Homo sapiens)
Triglyceride catabolism (Homo sapiens)
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
PLIN1 [lipid droplet] (Homo sapiens)
perilipin:CGI-58 complex -> perilipin + CGI-58 (Homo sapiens)
PLIN1 [lipid droplet] (Homo sapiens)
phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)
PLIN1 [lipid droplet] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
NR1H2 and NR1H3-mediated signaling (Homo sapiens)
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose (Homo sapiens)
Expression of PLIN1 regulated by NR1H2 or NR1H3 (Homo sapiens)
PLIN1 [lipid droplet] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60240 PLIN1
Gene Names
PLIN1, PERI, PLIN
Chain
chain:1-522
Reference Genes
BioGPS Gene:5346 PLIN1
COSMIC (genes):PLIN1 PLIN1
CTD Gene:5346 PLIN1
dbSNP Gene:5346 PLIN1
ENSEMBL:ENSG00000166819 PLIN1
ENSEMBL_homo_sapiens_GENE:ENSG00000166819.12 PLIN1
HGNC:9076 PLIN1
KEGG Gene (Homo sapiens):5346 PLIN1
Monarch:5346 PLIN1
NCBI Gene:5346 PLIN1
OMIM:170290 PLIN1
UCSC:O60240 PLIN1
Reference Transcript
RefSeq:NM_002666.4 PLIN1
RefSeq:XM_005254934.4 PLIN1
RefSeq:NM_001145311.1 PLIN1
Other Identifiers
11744311_a_at
11758374_s_at
16813173
205913_PM_at
205913_at
3638547
3638548
3638549
3638550
3638551
3638553
3638554
3638555
3638556
3638557
3638558
3638560
3638561
3638562
3638563
3638564
3638565
37122_at
5346
7991313
A_23_P26154
GE53123
GO:0005515
GO:0005783
GO:0005811
GO:0005829
GO:0006629
GO:0008289
GO:0016042
GO:0043226
GO:0070417
HMNXSV003009710
ILMN_1665562
PH_hs_0031487
TC15001834.hg
g4505884_3p_at
Participates
as an output of
Expression of PLIN1 regulated by NR1H2 or NR1H3 (Homo sapiens)
phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)
perilipin:CGI-58 complex -> perilipin + CGI-58 (Homo sapiens)
Expression of Perilipin (PLIN) (Homo sapiens)
as a component of
perilipin:CGI-58 complex [lipid droplet] (Homo sapiens)
as an input of
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
Other forms of this molecule
p-S81,S277-PLIN1 [lipid droplet]
Cross References
RefSeq
XP_005254991.1
,
NP_001138783.1
,
NP_002657.3
OpenTargets
ENSG00000166819
GeneCards
O60240
HPA
ENSG00000166819-PLIN1
Ensembl
ENSP00000402167
,
ENST00000300055
,
ENST00000430628
,
ENSP00000300055
,
ENSG00000166819
PRO
O60240
Pharos - Targets
O60240
Orphanet
20459
HMDB Protein
HMDBP02663
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14520 AQP7
1
AQP7 [plasma membrane]
(R-HSA-381264)
0.571
4
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