Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA

Stable Identifier
R-HSA-163676
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA
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Phosphorylation of ChREBP (Carbohydrate Response Element Binding Protein) at serine 196 by PKA inhibits its nuclear translocation. This reaction has been studied in detail using mouse proteins (Kawaguchi et al. 2001); the human version of the reaction is inferred from these studies.

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Output
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as an event of
Catalyst Activity

cAMP-dependent protein kinase activity of PKA catalytic subunit [cytosol]

Physical Entity
PKA catalytic subunit [cytosol] (Homo sapiens)
Activity
cAMP-dependent protein kinase activity (GO:0004691)
Inferred From
Phosphorylation of mpChREBP (Thr 666) at Ser(196) by mPKA (Mus musculus)
Authored
Gopinathrao, G  (2005-05-13)
Created
Gopinathrao, G  (2005-05-05)
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