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Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX
Stable Identifier
R-HSA-163748
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
,
endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
ChREBP activates metabolic gene expression (Homo sapiens)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the end of this reaction, 1 molecule of '1-acyl-sn-glycerol-3-phosphate acyltransferase alpha ' is present.
This reaction takes place in the 'nucleus' (Ma et al.2007).
Literature References
PubMed ID
Title
Journal
Year
17148476
A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription
Sham, YY
,
Towle, HC
,
Ma, L
,
Walters, KJ
Nucleic Acids Res.
2007
Participants
Output
AGPAT1 [endoplasmic reticulum membrane]
(Homo sapiens)
Participates
as an event of
ChREBP activates metabolic gene expression (Homo sapiens)
This event is regulated
Positively by
Regulator
ChREBP:MLX [nucleoplasm]
(Homo sapiens)
Orthologous Events
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Bos taurus)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Caenorhabditis elegans)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Canis familiaris)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Danio rerio)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Dictyostelium discoideum)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Drosophila melanogaster)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Gallus gallus)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Mus musculus)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Rattus norvegicus)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Saccharomyces cerevisiae)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Schizosaccharomyces pombe)
Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Sus scrofa)
Created
Gopinathrao, G (2005-05-06)
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