Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PROZ(24-40) [Golgi lumen]
Stable Identifier
R-HSA-163834
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
protein Z propeptide
Locations in the PathwayBrowser for interactor UniProt:Q9UK55 SERPINA10
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Homo sapiens)
Removal of aminoterminal propeptides from gamma-carboxylated proteins (Homo sapiens)
Furin cleaves pro-protein Z to protein Z (Homo sapiens)
PROZ(24-40) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22891 PROZ
Gene Names
PROZ
Chain
signal peptide:1-23, propeptide:24-40, chain:41-400
Reference Genes
BioGPS Gene:8858 PROZ
COSMIC (genes):PROZ PROZ
CTD Gene:8858 PROZ
dbSNP Gene:8858 PROZ
ENSEMBL:ENSG00000126231 PROZ
ENSEMBL_homo_sapiens_GENE:ENSG00000126231.15 PROZ
HGNC:9460 PROZ
KEGG Gene (Homo sapiens):8858 PROZ
Monarch:8858 PROZ
NCBI Gene:8858 PROZ
OMIM:176895 PROZ
UCSC:P22891 PROZ
Reference Transcript
RefSeq:NM_003891.2 PROZ
RefSeq:NM_001256134.1 PROZ
Other Identifiers
11738558_a_at
11744546_a_at
16776812
208034_PM_s_at
208034_s_at
3502477
3502478
3502479
3502480
3502482
3502483
3502485
3502488
3502490
3502491
3502492
3502493
3502494
37109_at
7970251
8858
A_23_P140074
GE53873
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0006508
GO:0007596
GO:0007599
GO:0016787
GO:0042060
GO:0043226
GO:0070062
GO:0140096
HMNXSV003040703
ILMN_1664565
M55671_at
PH_hs_0000128
TC13000418.hg
g4506120_3p_a_at
Participates
as an output of
Furin cleaves pro-protein Z to protein Z (Homo sapiens)
Other forms of this molecule
PROZ(24-400) [endoplasmic reticulum lumen]
13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen]
13xCbxE-PROZ(24-400) [Golgi lumen]
13xCbxE-PROZ [Golgi lumen]
Inferred To
proza [Golgi lumen]
(Danio rerio)
proz [Golgi lumen]
(Xenopus tropicalis)
PROZ(24-40) [Golgi lumen]
(Bos taurus)
PROZ(24-40) [Golgi lumen]
(Gallus gallus)
Proz [Golgi lumen]
(Mus musculus)
Proz [Golgi lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_003882.1
,
NP_001243063.1
OpenTargets
ENSG00000126231
GeneCards
P22891
HPA
ENSG00000126231-PROZ
Ensembl
ENST00000375547
,
ENSP00000344458
,
ENSP00000364697
,
ENST00000342783
,
ENSG00000126231
PRO
P22891
Pharos - Targets
P22891
Orphanet
22600
PDB
3F1S
,
3H5C
HMDB Protein
HMDBP02005
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UK55 SERPINA10
2
p-SERPINA10 [endoplasmic reticulum lumen]
(R-HSA-8956990)
SERPINA10 [endoplasmic reticulum lumen]
(R-HSA-8956739)
0.655
7
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text