Reactome | COX5A [mitochondrial inner membrane]

COX5A [mitochondrial inner membrane]

Stable Identifier

R-HSA-164308

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase polypeptide Va

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P20674 COX5A

Gene Names

COX5A

Chain

transit peptide:1-41, chain:42-150

Reference Genes

BioGPS Gene:9377 COX5A

COSMIC (genes):COX5A COX5A

CTD Gene:9377 COX5A

dbSNP Gene:9377 COX5A

ENSEMBL:ENSG00000178741 COX5A

ENSEMBL_homo_sapiens_GENE:ENSG00000178741.12 COX5A

HGNC:2267 COX5A

KEGG Gene (Homo sapiens):9377 COX5A

Monarch:9377 COX5A

NCBI Gene:9377 COX5A

OMIM:603773 COX5A

UCSC:P20674 COX5A

Reference Transcript

RefSeq:NM_004255.3 COX5A

Other Identifiers

11715656_at

16811739

203663_PM_s_at

203663_s_at

229426_PM_at

229426_at

3633222

3633223

3633225

3633226

3633227

3633232

3633233

41223_at

73621_at

7990436

9377

A_19_P00808453

GE81370

GE85800

GO:0003824

GO:0004129

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005751

GO:0006091

GO:0006119

GO:0006123

GO:0009055

GO:0016020

GO:0016491

GO:0031966

GO:0043226

GO:0045333

GO:0046872

GO:0055085

GO:1902600

HMNXSV003015635

Hs.181028.2.S1_3p_at

ILMN_1704477

M22760_at

PH_hs_0030032

TC15001652.hg

g4758037_3p_a_at

Participates

as a member of

Substrate of AFG3L2 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

Other forms of this molecule

COX5A [mitochondrial intermembrane space]

Inferred To

Cox5a [mitochondrial inner membrane] (Mus musculus)

Cox5a [mitochondrial inner membrane] (Rattus norvegicus)

cox6 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

cox-5A [mitochondrial inner membrane] (Caenorhabditis elegans)

cox5aa [mitochondrial inner membrane] (Danio rerio)

COX5A [mitochondrial inner membrane] (Bos taurus)

COX5A [mitochondrial inner membrane] (Canis familiaris)

COX5A [mitochondrial inner membrane] (Drosophila melanogaster)

COX5A [mitochondrial inner membrane] (Gallus gallus)

COX5A [mitochondrial inner membrane] (Sus scrofa)

cox5a [mitochondrial inner membrane] (Xenopus tropicalis)

COX6 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_004246.2

OpenTargets

ENSG00000178741

HPA

ENSG00000178741-COX5A

GeneCards

P20674

Ensembl

ENSP00000456386, ENST00000564811, ENSG00000178741, ENST00000322347, ENSP00000317780

PRO

P20674

Pharos - Targets

P20674

Orphanet

25447

HMDB Protein

HMDBP03108

PDB

5Z62

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00403 MT-CO2	2	nascent MT-CO2 [mitochondrial matrix] (R-HSA-9902095) nascent MT-CO2 [mitochondrial inner membrane] (R-HSA-164302)	0.564	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3

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