Reactome | COX8A [mitochondrial inner membrane]

COX8A [mitochondrial inner membrane]

Stable Identifier

R-HSA-164313

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase polypeptide VIII, Cytochrome c oxidase subunit 8-2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P10176 COX8A

Gene Names

COX8A, COX8, COX8L

Chain

transit peptide:1-25, chain:26-69

Reference Genes

BioGPS Gene:1351 COX8A

COSMIC (genes):COX8A COX8A

CTD Gene:1351 COX8A

dbSNP Gene:1351 COX8A

ENSEMBL:ENSG00000176340 COX8A

ENSEMBL_homo_sapiens_GENE:ENSG00000176340.4 COX8A

HGNC:2294 COX8A

KEGG Gene (Homo sapiens):1351 COX8A

Monarch:1351 COX8A

NCBI Gene:1351 COX8A

OMIM:123870 COX8A

Reference Transcript

RefSeq:NM_004074.2 COX8A

Other Identifiers

11715458_a_at

11715459_x_at

1351

16726183

201119_PM_s_at

201119_s_at

3334126

3334127

3334130

3334131

3334132

3334133

3334134

38080_at

7940835

ADDON002451.hg

A_23_P52639

GE488941

GO:0003824

GO:0004129

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005751

GO:0006091

GO:0006119

GO:0006123

GO:0016020

GO:0016491

GO:0031966

GO:0043226

GO:0045277

GO:0045333

GO:0055085

GO:1902600

HMNXSV003026582

ILMN_1809495

J04823_rna1_at

PH_hs_0020157

TC11003499.hg

g4758043_3p_a_at

Participates

as a component of

Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Ghost homologue of COX8A [mitochondrial inner membrane] (Danio rerio)

Ghost homologue of COX8A [mitochondrial inner membrane] (Xenopus tropicalis)

Cox8a [mitochondrial inner membrane] (Mus musculus)

Cox8a [mitochondrial inner membrane] (Rattus norvegicus)

COX8A [mitochondrial inner membrane] (Canis familiaris)

COX8A [mitochondrial inner membrane] (Gallus gallus)

COX8A [mitochondrial inner membrane] (Sus scrofa)

COX8 [mitochondrial inner membrane] (Drosophila melanogaster)

LOC783202 [mitochondrial inner membrane] (Bos taurus)

Cross References

RefSeq

NP_004065.1

OpenTargets

ENSG00000176340

HPA

ENSG00000176340-COX8A

GeneCards

P10176

Ensembl

ENSP00000321260, ENSG00000176340, ENST00000314133

PRO

P10176

Pharos - Targets

P10176

Orphanet

23674

PDB

8D4T, 5Z62

HMDB Protein

HMDBP03270

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.556	3