Reactome | ATP5J [mitochondrial inner membrane]

ATP5J [mitochondrial inner membrane]

Stable Identifier

R-HSA-164532

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase coupling factor 6

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5J [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5J [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P18859 ATP5PF

Gene Names

ATP5PF, ATP5A, ATP5J, ATPM

Chain

transit peptide:1-32, chain:33-108

Reference Genes

BioGPS Gene:522 ATP5PF

COSMIC (genes):ATP5PF ATP5PF

CTD Gene:522 ATP5PF

dbSNP Gene:522 ATP5PF

ENSEMBL:ENSG00000154723 ATP5J

ENSEMBL_homo_sapiens_GENE:ENSG00000154723.13 ATP5PF

HGNC:847 ATP5PF

KEGG Gene (Homo sapiens):522 ATP5PF

Monarch:522 ATP5PF

NCBI Gene:522 ATP5PF

OMIM:603152 ATP5PF

UCSC:P18859 ATP5PF

Reference Transcript

Other Identifiers

11715744_a_at

16924537

202325_PM_s_at

202325_s_at

36107_at

3927179

3927180

3927181

3927182

3927184

3927185

3927186

3927188

3927190

3927191

3927192

3927193

3927194

3927195

3927196

3927197

522

8069633

GE81056

GO:0000276

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005753

GO:0006091

GO:0006811

GO:0015078

GO:0015986

GO:0016020

GO:0016874

GO:0021762

GO:0042776

GO:0043226

GO:0045263

GO:0046933

GO:0048856

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003010310

ILMN_1652806

ILMN_1772929

ILMN_2348093

M37104_at

PH_hs_0023210

g4502292_3p_a_at

Participates

as a member of

Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ATP5PF [mitochondrial inner membrane] (Bos taurus)

Ghost homologue of ATP5J [mitochondrial inner membrane] (Saccharomyces cerevisiae)

ATPsynCF6 [mitochondrial inner membrane] (Drosophila melanogaster)

Atp5pf [mitochondrial inner membrane] (Mus musculus)

Atp5pf [mitochondrial inner membrane] (Rattus norvegicus)

atp-4 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP5J [mitochondrial inner membrane] (Canis familiaris)

ATP5J [mitochondrial inner membrane] (Gallus gallus)

ATP5J [mitochondrial inner membrane] (Sus scrofa)

atp5j [mitochondrial inner membrane] (Danio rerio)

Cross References

RefSeq

NP_001003697.1, NP_001307196.1, NP_001003701.1, NP_001003696.1, NP_001003703.1, NP_001676.2, NP_001307195.1

Guide to Pharmacology - Targets

807

OpenTargets

ENSG00000154723

GeneCards

P18859

HPA

ENSG00000154723-ATP5PF

Ensembl

ENSP00000382966, ENSP00000382959, ENSP00000382965, ENSP00000284971, ENSG00000154723, ENST00000284971, ENST00000400090, ENSP00000389649, ENST00000400093, ENST00000400094, ENST00000457143, ENSP00000382962, ENST00000400087

PRO

P18859

Pharos - Targets

P18859

HMDB Protein

HMDBP01282

PDB

8H9V, 8H9S, 8H9G, 8H9K, 8H9T, 8H9R, 8H9N, 8H9U

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	4