Expression of Lanosterol Demethylase (CYP51A1)

Stable Identifier
R-HSA-1655847
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The CYP51A1 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the Lanosterol Demethylase (CYP51A1) gene and enhance transcription (Pai et al. 1998, Sakakura et al. 2001, Halder et al. 2002, Reed et al. 2008, reviewed in Horton et al. 2002).
Literature References
PubMed ID Title Journal Year
8619637 The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols

Stromstedt, M, Waterman, MR, Rozman, D

Arch Biochem Biophys 1996
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