PIPs transport between plasma and early endosome membranes

Stable Identifier
R-HSA-1660524
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PIPs transport between plasma and early endosome membranes
Click the image above or here to open this pathway in the Pathway Browser
The phosphoinositide phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) translocates from the plasma membrane to the early endosome membrane (Watt et al. 2004, Ivetac et al. 2005).
Literature References
PubMed ID Title Journal Year
15716355 The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane

Luff, S, Majerus, PW, Kisseleva, MV, Rowe, T, Zhang, XM, Tiganis, T, Munday, AD, Ivetac, I, Mitchell, CA, Whisstock, JC

Mol Biol Cell 2005
14604433 Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

Leslie, NR, Kimber, WA, Lucocq, JM, Downes, CP, Watt, SA, Fleming, IN

Biochem J 2004
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
phospholipid translocation (0045332)
Authored
Williams, MG  (2011-10-18)
Reviewed
Wakelam, M  (2012-05-14)
Created
Williams, MG  (2011-10-13)
Cite Us!