Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MYD88 [cytosol]
Stable Identifier
R-HSA-166059
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MyD88
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
Hyperphosphorylated IRAK1 associates with TRAF6 (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP binds MYD88 homodimer (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK1 binds to MYD88 within the IL1R complex (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK4 is activated by autophosphorylation (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK4 phosphorylates IRAK1 (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-S376,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK4-activated IRAK1 autophosphorylates (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-S376,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
TRAF6 binding leads to IRAK1:TRAF6 release (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
The Interleukin 1 receptor complex binds Tollip (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Homo sapiens)
IL1R1:IL1:IL1RAP:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Homo sapiens)
DHX36 or DHX9 binds MyD88 (Homo sapiens)
DHX9/DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
DHX9:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)
DHX9:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
p-IRF7:p-IRF7 translocates to the nucleus (Homo sapiens)
DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
RIP-mediated NFkB activation via ZBP1 (Homo sapiens)
NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)
DHX9:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
p75NTR signals via NF-kB (Homo sapiens)
p75NTR recruits signalling complexes (Homo sapiens)
IRAK interacts with TRAF6 (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
IRAK is activated (Homo sapiens)
NGF ligand:p75NTR:IRAK1:MYD88 [plasma membrane] (Homo sapiens)
IRAK1:MYD88 [cytosol] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
MYD88 dissociates (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Homo sapiens)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
p75NTR interacts with IRAK:MYD88 (Homo sapiens)
IRAK1:MYD88 [cytosol] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
NGF ligand:p75NTR:IRAK1:MYD88 [plasma membrane] (Homo sapiens)
IRAK1:MYD88 [cytosol] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Homo sapiens)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Homo sapiens)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
MYD88 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99836 MYD88
Gene Names
MYD88
Chain
chain:1-296
Reference Genes
COSMIC (genes):MYD88 MYD88
dbSNP Gene:4615 MYD88
ENSEMBL:ENSG00000172936 MYD88
Participates
as a component of
DHX9:CpG:MyD88 [cytosol] (Homo sapiens)
DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
MYD88 dimer [cytosol] (Homo sapiens)
as an input of
DHX36 or DHX9 binds MyD88 (Homo sapiens)
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
Other forms of this molecule
MyD88 R196C [cytosol]
MyD88 E52del [cytosol]
MyD88 L93P [cytosol]
MyD88 S34Y [cytosol]
MyD88 E65del [cytosol]
MYD88 [endosome membrane]
MYD88 [plasma membrane]
Inferred To
Myd88 [cytosol]
(Drosophila melanogaster)
Myd88 [cytosol]
(Mus musculus)
Myd88 [cytosol]
(Rattus norvegicus)
MYD88 [cytosol]
(Bos taurus)
MYD88 [cytosol]
(Canis familiaris)
MYD88 [cytosol]
(Gallus gallus)
MYD88 [cytosol]
(Sus scrofa)
myd88 [cytosol]
(Danio rerio)
myd88 [cytosol]
(Xenopus tropicalis)
Interactors (24)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99836 MYD88
8
MyD88 R196C [cytosol]
(R-HSA-5602329)
MyD88 E52del [cytosol]
(R-HSA-5602451)
MyD88 L93P [cytosol]
(R-HSA-5602612)
MyD88 S34Y [cytosol]
(R-HSA-5602521)
MyD88 E65del [cytosol]
(R-HSA-5602598)
MYD88 [endosome membrane]
(R-HSA-975123)
MYD88 [plasma membrane]
(R-HSA-937017)
MYD88 [cytosol]
(R-HSA-166059)
0.958
40
UniProt:Q9NWZ3 IRAK4
9
IRAK4 [cytosol]
(R-HSA-166081)
p-T342,T345,S346-IRAK4 [plasma membrane]
(R-HSA-936957)
IRAK4 [plasma membrane]
(R-HSA-937051)
p-T342,T345,S346-IRAK4 [endosome membrane]
(R-HSA-975149)
IRAK4 [endosome membrane]
(R-HSA-975167)
p-T342,T345,S346-IRAK4 [cytosol]
(R-HSA-446649)
IRAK4 E402* [cytosol]
(R-HSA-5602517)
IRAK4 R12C [cytosol]
(R-HSA-5602511)
IRAK4 Q293* [cytosol]
(R-HSA-5602426)
0.922
15
UniProt:P58753 TIRAP
2
TIRAP [cytosol]
(R-HSA-166141)
p-4Y-TIRAP [plasma membrane]
(R-HSA-2201321)
0.861
9
UniProt:O43791 SPOP
1
SPOP [nucleoplasm]
(R-HSA-5635035)
0.837
8
UniProt:O00206 TLR4
2
TLR4 [endosome membrane]
(R-HSA-2201285)
2xN4GlycoAsn-TLR4 [plasma membrane]
(R-HSA-166045)
0.758
4
UniProt:O60603 TLR2
3
TLR2 [plasma membrane]
(R-HSA-167992)
TLR2 [secretory granule membrane]
(R-HSA-6804777)
TLR2 [plasma membrane]
(R-HSA-9637646)
0.737
4
UniProt:P51617 IRAK1
14
IRAK1 [cytosol]
(R-HSA-446639)
p-2S,S376,T,T209,T387-IRAK1 [cytosol]
(R-HSA-446682)
p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
(R-HSA-937011)
p-T209,T387-IRAK1 [plasma membrane]
(R-HSA-166279)
p-T209-IRAK1 [plasma membrane]
(R-HSA-937031)
IRAK1 [plasma membrane]
(R-HSA-937045)
p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
(R-HSA-975157)
IRAK1 [endosome membrane]
(R-HSA-975127)
p-T209,T387-IRAK1 [endosome membrane]
(R-HSA-975117)
p-T209-IRAK1 [endosome membrane]
(R-HSA-975189)
K63polyUb-hp-IRAK1 [cytosol]
(R-HSA-451565)
p-S376,T387-IRAK1 [cytosol]
(R-HSA-446687)
K63polyUb-hp-IRAK1 [endosome membrane]
(R-HSA-975112)
p-S,T-IRAK1 [cytosol]
(R-HSA-3149574)
0.723
4
UniProt:O14836 TNFRSF13B
1
TAC1 [plasma membrane]
(R-HSA-5668752)
0.692
12
UniProt:Q6SZW1 SARM1
0.622
5
UniProt:P10599 TXN
4
TXN [cytosol]
(R-HSA-66000)
2xHC-TXN [cytosol]
(R-HSA-73668)
TXN [nucleoplasm]
(R-HSA-9617732)
2xHC-TXN [nucleoplasm]
(R-HSA-9617733)
0.602
4
UniProt:Q8NF50 DOCK8
1
DOCK8 [cytosol]
(R-HSA-1011619)
0.576
3
UniProt:Q13158 FADD
1
FADD [cytosol]
(R-HSA-54639)
0.573
3
UniProt:P13682 ZNF35
0.556
3
UniProt:Q69FE3 Q69FE3
0.556
5
UniProt:P78317 RNF4
2
RNF4 [nucleoplasm]
(R-HSA-5684076)
RNF4 [cytosol]
(R-HSA-975974)
0.556
3
UniProt:P38340 NTM1
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:Q6IQ16 SPOPL
1
SPOPL [nucleoplasm]
(R-HSA-5635036)
0.556
3
UniProt:P84022 SMAD3
20
p-S423,S425-SMAD3 [nucleoplasm]
(R-HSA-177104)
p-S423,S425-SMAD3 [cytosol]
(R-HSA-171184)
SMAD3 [cytosol]
(R-HSA-170855)
p-T179,S423,S425-SMAD3 [nucleoplasm]
(R-HSA-2176471)
Ub,p-T179,S423,S425-SMAD3 [nucleoplasm]
(R-HSA-9773841)
2xADPRib-p-S423,S425-SMAD3 [nucleoplasm]
(R-HSA-2187326)
SMAD3 [nucleoplasm]
(R-HSA-206150)
p-S208-SMAD3 [cytosol]
(R-HSA-9731114)
SMAD3 S425C [cytosol]
(R-HSA-3308499)
SMAD3 Y298* [cytosol]
(R-HSA-9668769)
SMAD3 R368* [cytosol]
(R-HSA-9668768)
SMAD3 E383* [cytosol]
(R-HSA-9668775)
SMAD3 S425F [cytosol]
(R-HSA-8944158)
SMAD3 Q322* [cytosol]
(R-HSA-9668773)
SMAD3 Q358* [cytosol]
(R-HSA-9668772)
SMAD3 E246* [cytosol]
(R-HSA-9668776)
SMAD3 W326* [cytosol]
(R-HSA-9668766)
SMAD3 Y384* [cytosol]
(R-HSA-9668782)
SMAD3 Q316* [cytosol]
(R-HSA-9668765)
p-S423,S425-SMAD3 R268H [cytosol]
(R-HSA-3315080)
0.543
3
UniProt:Q93009 USP7
2
USP7 [nucleoplasm]
(R-HSA-3215278)
USP7 [cytosol]
(R-HSA-8853511)
0.543
3
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.543
3
UniProt:Q9UGK3 STAP2
2
STAP2 [cytosol]
(R-HSA-8848028)
p-Y250-STAP2 [plasma membrane]
(R-HSA-8848079)
0.524
3
UniProt:Q9UBN7 HDAC6
4
HDAC6 [lysosomal lumen]
(R-HSA-9660002)
HDAC6 [cytosol]
(R-HSA-5324660)
HDAC6 [late endosome lumen]
(R-HSA-9659980)
HDAC6 [nucleoplasm]
(R-HSA-351589)
0.524
6
UniProt:Q15109 AGER
1
AGER [plasma membrane]
(R-HSA-197639)
0.462
8
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text