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Limited elongation of the HIV-1 transcript
Stable Identifier
R-HSA-167087
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
HIV Transcription Elongation (Homo sapiens)
Abortive elongation of HIV-1 transcript in the absence of Tat (Homo sapiens)
Limited elongation of the HIV-1 transcript (Homo sapiens)
General
SBML
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SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
In the absence of Tat, transcriptional elongation beyond position +59 does not occur (Kao et al., 1987).
Literature References
PubMed ID
Title
Journal
Year
2825027
Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
Peterlin, BM
,
Luciw, PA
,
Kao, SY
,
Calman, AF
Nature
1987
Participants
Input
DSIF:NELF:early elongation complex [nucleoplasm]
(Homo sapiens)
NTP [nucleoplasm]
Output
DSIF:NELF:early elongation complex after limited nucleotide addition [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Abortive elongation of HIV-1 transcript in the absence of Tat (Homo sapiens)
Inferred From
Addition of nucleotides leads to transcript elongation (Homo sapiens)
Disease
Name
Identifier
Synonyms
Human immunodeficiency virus infectious disease
DOID:526
HIV infection
Authored
Matthews, L (2005-07-27)
Rice, AP (2005-07-27)
Created
Matthews, L (2005-10-11)
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