Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ABI [cytosol]
Stable Identifier
R-HSA-1671649
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
WAVE2 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
WAVE2 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
WAVE1 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
WAVE1 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
WAVE2 Regulatory Complex [cytosol] (Homo sapiens)
ABI [cytosol] (Homo sapiens)
Participants
members
ABI1 [cytosol]
(Homo sapiens)
candidates
ABI2 [cytosol]
(Homo sapiens)
Participates
as a component of
WAVE1 Regulatory Complex [cytosol] (Homo sapiens)
WAVE2 Regulatory Complex [cytosol] (Homo sapiens)
p-Y-WRC [cytosol] (Homo sapiens)
WAVE Regulatory Complex [cytosol] (Homo sapiens)
Inferred To
abi-1 [cytosol]
(Caenorhabditis elegans)
ABI [cytosol]
(Bos taurus)
ABI [cytosol]
(Canis familiaris)
ABI [cytosol]
(Gallus gallus)
ABI [cytosol]
(Mus musculus)
ABI [cytosol]
(Rattus norvegicus)
ABI [cytosol]
(Sus scrofa)
ABI [cytosol]
(Xenopus tropicalis)
Abi [cytosol]
(Drosophila melanogaster)
abiA [cytosol]
(Dictyostelium discoideum)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
