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Abortive HIV-1 Initiation After Second Transition
Stable Identifier
R-HSA-167468
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Abortive HIV-1 Initiation After Second Transition (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'HIV-1 transcription complex containing 4-9 nucleotide long transcript' is present. At the end of this reaction, 1 molecule of 'TFIIH', 1 molecule of 'TFIIE', 1 molecule of 'HIV-1 template DNA:4-9 nucleotide transcript hybrid', and 1 molecule of 'RNA Polymerase II (unphosphorylated):TFIIF complex' are present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
1939271
Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.
Luse, SW
,
Jacob, GA
,
Luse, DS
J Biol Chem
1991
Participants
Input
HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm]
(Homo sapiens)
Output
HIV-1 template DNA:4-9 nucleotide transcript hybrid [nucleoplasm]
(Human immunodeficiency virus 1)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
(Homo sapiens)
TFIIE [nucleoplasm]
(Homo sapiens)
TFIIH [nucleoplasm]
(Homo sapiens)
Participates
as an event of
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Inferred From
Abortive Initiation After Second Transition (Homo sapiens)
Disease
Name
Identifier
Synonyms
Human immunodeficiency virus infectious disease
DOID:526
HIV infection
Authored
Matthews, L (2005-07-27)
Rice, AP (2005-07-27)
Created
Matthews, L (2005-10-18)
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