Ribonucleoprotein release from M1 proteins

Stable Identifier
R-HSA-168299
Type
Reaction
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
cytosol, endocytic vesicle membrane, endosome lumen
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Ribonucleoprotein release from M1 proteins
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The influx of H+ ions into the virion disrupts protein-protein interactions, resulting in the release of the viral RNP from the viral matrix (M1) protein. The uncoating process is complete with the appearance of free RNP complexes in the cytosol.

Literature References
PubMed ID Title Journal Year
1985199 Transport of incoming influenza virus nucleocapsids into the nucleus

Martin, K, Helenius, A

J Virol 1991
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
uncoating of virus (0019061)
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
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