ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2

Stable Identifier
R-HSA-169270
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Transfer of electrons from ETF to ubiquinone by ETF-QO
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ETF-ubiquinone oxidoreductase (ETFDH), catalyses the re-oxidation of reduced ETF, with ubiquinone (CoQ) as the electron acceptor being reduced to ubiquinol (QH2) (Estornell et al. 1992, MacLennan et al. 1997).

Literature References
PubMed ID Title Journal Year
4288886 Studies on the mechanims of oxidative phosphorylation. IX. Effect of cytochrome c on energy-linked processes

Szarkowska, L, Lenaz, G, MacLennan, DH

J. Biol. Chem. 1966
1327877 Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria

Cavazzoni, M, Parenti Castelli, G, Estornell, E, Lenaz, G, Fato, R, Castelluccio, C

FEBS Lett. 1992
Participants
Participates
Catalyst Activity

electron-transferring-flavoprotein dehydrogenase activity of ETFDH [mitochondrial matrix]

Orthologous Events
Created
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