MCM8 mediated fork unwinding

Stable Identifier
R-HSA-169461
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MCM8 mediated fork unwinding
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The MCM2-7 related protein, MCM8, is required to replicate chromosomal DNA in Xenopus egg extracts. MCM8 binds chromatin upon initiation of DNA synthesis. It may function as an helicase in the elongation step.
Participants
Input
Output
Participates
as an event of
Catalyst Activity

helicase activity of MCM8 [nucleoplasm]

Physical Entity
MCM8 [nucleoplasm] (Homo sapiens)
Activity
helicase activity (GO:0004386)
Inferred From
Xenopus Mcm8 mediated fork unwinding (Xenopus laevis)
Authored
Tye, BK  (2005-11-29)
Created
Gopinathrao, G  (2005-11-29)
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