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p-Y1095-KIDINS220 [cytosol]
Stable Identifier
R-HSA-169869
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Phospho-ARMS/KIDINS220 protein
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
ARMS-mediated activation (Homo sapiens)
ARMS is phosphorylated by active TrkA receptor (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
BRAF in Rap1-GTP complex:BRAF complex autophosphorylates (Homo sapiens)
Rap1-GTP complex:BRAF complex [plasma membrane] (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
Rap1-GTP complex:p-S,T-BRAF complex [plasma membrane] (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
Crk's SH3 domain engages C3G (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
Rap1-GTP complex binds BRAF complex (Homo sapiens)
Rap1-GTP complex [plasma membrane] (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
Rap1-GTP complex:BRAF complex [plasma membrane] (Homo sapiens)
Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] (Homo sapiens)
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
p-Y1095-KIDINS220 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULH0 KIDINS220
Gene Names
KIDINS220, ARMS, KIAA1250
Chain
chain:1-1771
Reference Genes
BioGPS Gene:57498 KIDINS220
COSMIC (genes):KIDINS220 KIDINS220
CTD Gene:57498 KIDINS220
dbSNP Gene:57498 KIDINS220
ENSEMBL:ENSG00000134313 KIDINS220
HGNC:29508 KIDINS220
KEGG:hsa:57498 KIDINS220
Monarch:57498 KIDINS220
NCBI Gene:57498 KIDINS220
OMIM:615759 KIDINS220
UCSC:Q9ULH0 KIDINS220
Reference Transcript
RefSeq:NM_020738.2 KIDINS220
Other Identifiers
11743331_a_at
11745889_a_at
11746232_a_at
11750597_a_at
1557246_3p_at
1557246_PM_at
1557246_at
16894235
212162_PM_at
212162_at
212163_PM_at
212163_at
214932_PM_at
214932_at
236166_PM_at
236166_at
242032_PM_at
242032_at
242852_PM_at
242852_at
2539519
2539521
2539523
2539524
2539525
2539526
2539527
2539528
2539529
2539530
2539531
2539532
2539533
2539534
2539535
2539537
2539538
2539539
2539540
2539541
2539544
2539545
2539546
2539547
2539548
2539549
2539550
2539551
2539552
2539553
2539554
2539555
2539557
2539558
2539559
2539560
2539561
2539563
2539564
2539565
2539569
2539570
2539571
2539572
2539573
2539574
2539576
2539577
2539578
2539579
2539580
2539581
2539582
2539583
2539584
2539585
2539586
2539587
2539588
2539589
2539591
2539592
2539593
2539594
2539595
2539596
2539597
2539598
2539599
2539600
2539602
3363691
39163_at
52515_at
57498
59269_at
66878_r_at
79108_i_at
79109_r_at
79111_at
8050128
A_23_P131747
A_24_P7202
A_24_P97145
A_33_P3579984
GE505854
GE53851
GE592069
GE646209
GE763703
GO:0001701
GO:0005515
GO:0005768
GO:0005770
GO:0005829
GO:0007399
GO:0010976
GO:0016020
GO:0019887
GO:0030165
GO:0031410
GO:0032991
GO:0038180
GO:0043226
GO:0048813
GO:0048856
GO:0098772
GO:1990090
HMNXSV003017800
HMNXSV003041839
Hs.137182.0.A1_3p_at
Hs.153460.0.A1_3p_at
Hs.22657.0.S1_3p_at
Hs.9873.0.S1_3p_at
Hs.9873.0.S2_3p_at
Hs.9873.1.S1_3p_at
Hs2.129874.1.S1_3p_s_at
ILMN_1679232
ILMN_1902594
PH_hs_0001022
PH_hs_0019365
TC02001555.hg
TC02004034.hg
p9011
Participates
as a component of
Phospho-ARMS:Crk [cytosol] (Homo sapiens)
Other forms of this molecule
KIDINS220 [cytosol]
Inferred To
phospho-kidins220 [cytosol]
(Xenopus tropicalis)
phospho-p-Y1095-KIDINS220 [cytosol]
(Gallus gallus)
phospho-kidins220b [cytosol]
(Danio rerio)
phospho-KIDINS220 [cytosol]
(Bos taurus)
phospho-KIDINS220 [cytosol]
(Canis familiaris)
phospho-KIDINS220 [cytosol]
(Sus scrofa)
phospho-Kidins220 [cytosol]
(Mus musculus)
phospho-Kidins220 [cytosol]
(Rattus norvegicus)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1095
Coordinate
1095
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_065789.1
ENSEMBL
ENSP00000510510
,
ENSP00000256707
,
ENST00000256707
,
ENST00000685097
,
ENST00000319688
,
ENSP00000319947
,
ENSP00000418974
,
ENST00000473731
OpenTargets
ENSG00000134313
HPA
ENSG00000134313-KIDINS220
PRO
Q9ULH0
Pharos - Targets
Q9ULH0
GlyGen
Q9ULH0
Orphanet
KIDINS220
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P34925 RYK
1
RYK [plasma membrane]
(R-HSA-3006746)
0.483
2
UniProt:P21802 FGFR2
20
FGFR2 IIIa TM [extracellular region]
(R-HSA-8851703)
FGFR2 [plasma membrane]
(R-HSA-2023840)
FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane]
(R-HSA-8853137)
FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane]
(R-HSA-8853154)
FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane]
(R-HSA-8853123)
FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane]
(R-HSA-8853158)
FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane]
(R-HSA-8853150)
FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane]
(R-HSA-8853153)
FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane]
(R-HSA-8853139)
FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane]
(R-HSA-8853159)
FGFR2 N549H [plasma membrane]
(R-HSA-2033296)
FGFR2 N549K [plasma membrane]
(R-HSA-1637910)
FGFR2 K660N [plasma membrane]
(R-HSA-1637905)
p-8Y-FGFR2 K660M [plasma membrane]
(R-HSA-2033300)
p-8Y-FGFR2 K660E [plasma membrane]
(R-HSA-2033298)
phosphorylated FGFR2 L764Hfs*4 [plasma membrane]
(R-HSA-2071957)
p-8Y-FGFR2 W290C [plasma membrane]
(R-HSA-2029875)
p-8Y-FGFR2 S267P [plasma membrane]
(R-HSA-2029879)
p-8Y-FGFR2 [plasma membrane]
(R-HSA-2029874)
p-8Y-FGFR2 N549K [plasma membrane]
(R-HSA-2033306)
0.483
2
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